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Shan Yu
Shan Yu
Takeda Pharmaceuticals
Verified email at takeda.com
Title
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Cited by
Year
Decarboxylative borylation
C Li, J Wang, LM Barton, S Yu, M Tian, DS Peters, M Kumar, AW Yu, ...
Science 356 (6342), eaam7355, 2017
3652017
Regulation of macrophage arginase expression and tumor growth by the Ron receptor tyrosine kinase
DR Sharda, S Yu, M Ray, ML Squadrito, M De Palma, TA Wynn, ...
The Journal of Immunology 187 (5), 2181-2192, 2011
1922011
Dietary cocoa ameliorates obesity-related inflammation in high fat-fed mice
Y Gu, S Yu, JD Lambert
European journal of nutrition 53, 149-158, 2014
1342014
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages
ED Muse, S Yu, CR Edillor, J Tao, NJ Spann, TD Troutman, JS Seidman, ...
Proceedings of the National Academy of Sciences 115 (20), E4680-E4689, 2018
982018
Dietary cocoa reduces metabolic endotoxemia and adipose tissue inflammation in high-fat fed mice
Y Gu, S Yu, JY Park, K Harvatine, JD Lambert
The Journal of nutritional biochemistry 25 (4), 439-445, 2014
882014
Targeted delivery of LXR agonist using a site-specific antibody–drug conjugate
RKV Lim, S Yu, B Cheng, S Li, NJ Kim, Y Cao, V Chi, JY Kim, ...
Bioconjugate chemistry 26 (11), 2216-2222, 2015
752015
Inhibition of TLR4-induced IκB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein
M Ray, S Yu, DR Sharda, CB Wilson, QP Liu, N Kaushal, KS Prabhu, ...
The Journal of Immunology 185 (12), 7309-7316, 2010
612010
Neratinib protects pancreatic beta cells in diabetes
A Ardestani, S Li, K Annamalai, B Lupse, S Geravandi, A Dobrowolski, ...
Nature communications 10 (1), 5015, 2019
532019
Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody–drug conjugate
S Yu, AD Pearson, RKV Lim, DT Rodgers, S Li, HB Parker, M Weglarz, ...
Molecular Therapy 24 (12), 2078-2089, 2016
502016
Dissociated sterol-based liver X receptor agonists as therapeutics for chronic inflammatory diseases
S Yu, S Li, A Henke, ED Muse, B Cheng, G Welzel, AK Chatterjee, ...
The FASEB Journal 30 (7), 2570, 2016
302016
Regulation of alternative macrophage activation in the liver following acetaminophen intoxication by stem cell-derived tyrosine kinase
CR Gardner, P Hankey, V Mishin, M Francis, S Yu, JD Laskin, DL Laskin
Toxicology and applied pharmacology 262 (2), 139-148, 2012
292012
The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis
S Yu, JN Allen, A Dey, L Zhang, G Balandaram, MJ Kennett, M Xia, ...
The Journal of Immunology 197 (1), 256-265, 2016
232016
Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation
JN Allen, A Dey, R Nissly, J Fraser, S Yu, G Balandaram, JM Peters, ...
JoVE (Journal of Visualized Experiments), e55445, 2017
172017
The virtual element in proximal promoter of porcine myostatin is regulated by myocyte enhancer factor 2C
J Li, J Deng, S Yu, J Zhang, D Cheng, H Wang
Biochemical and biophysical research communications 419 (2), 175-181, 2012
162012
Design of a long-acting and selective MEG-fatty acid stapled prolactin-releasing peptide analog
E Pflimlin, S Lear, C Lee, S Yu, H Zou, A To, S Joseph, V Nguyen-Tran, ...
ACS Medicinal Chemistry Letters 10 (8), 1166-1172, 2019
102019
A novel inhibitor of inducible NOS dimerization protects against cytokine‐induced rat beta cell dysfunction
L Zhong, T Tran, TD Baguley, SJ Lee, A Henke, A To, S Li, S Yu, ...
British Journal of Pharmacology 175 (17), 3470-3485, 2018
82018
Next horizons: ADCs beyond oncology
S Yu, A Lim, MS Tremblay
Innovations for Next-Generation Antibody-Drug Conjugates, 321-347, 2018
82018
Liver x receptor agonists and uses thereof
S Pinkerton, MS Tremblay, AK Chatterjee, B Cheng, KV Reyna, S Yu, ...
US Patent App. 15/147,863, 2016
62016
Ex Vivo Cell-Based Screening Platform for Modulators of Hepatosteatosis
S Yu, E Chen, L Sherwood, M Hull, AK Woods, MS Tremblay
ACS Chemical Biology 12 (7), 1937-1946, 2017
32017
Development of novel sterol-based Liver X Receptor agonists as therapeutics for inflammatory diseases (HUM1P. 307)
S Yu, S Li, A Henke, G Welzel, S Li, B Cheng, M Evan, C Glass, ...
The Journal of Immunology 194 (1_Supplement), 52.32-52.32, 2015
22015
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