Trifluoroethanol-induced stabilization of the α-helical structure of β-lactoglobulin: implication for non-hierarchical protein folding K Shiraki, K Nishikawa, Y Goto Journal of molecular biology 245 (2), 180-194, 1995 | 554 | 1995 |
Biophysical effect of amino acids on the prevention of protein aggregation K Shiraki, M Kudou, S Fujiwara, T Imanaka, M Takagi The Journal of Biochemistry 132 (4), 591-595, 2002 | 315 | 2002 |
Effect of additives on protein aggregation H Hamada, T Arakawa, K Shiraki Current pharmaceutical biotechnology 10 (4), 400-407, 2009 | 305 | 2009 |
Chemical modification of amino acids by atmospheric-pressure cold plasma in aqueous solution E Takai, T Kitamura, J Kuwabara, S Ikawa, S Yoshizawa, K Shiraki, ... Journal of Physics D: Applied Physics 47 (28), 285403, 2014 | 280 | 2014 |
Protein inactivation by low‐temperature atmospheric pressure plasma in aqueous solution E Takai, K Kitano, J Kuwabara, K Shiraki Plasma Processes and Polymers 9 (1), 77-82, 2012 | 189 | 2012 |
Prevention of thermal inactivation and aggregation of lysozyme by polyamines M Kudou, K Shiraki, S Fujiwara, T Imanaka, M Takagi European Journal of Biochemistry 270 (22), 4547-4554, 2003 | 165 | 2003 |
Specific decrease in solution viscosity of antibodies by arginine for therapeutic formulations N Inoue, E Takai, T Arakawa, K Shiraki Molecular pharmaceutics 11 (6), 1889-1896, 2014 | 120 | 2014 |
Mechanistic insights into protein precipitation by alcohol H Yoshikawa, A Hirano, T Arakawa, K Shiraki International journal of biological macromolecules 50 (3), 865-871, 2012 | 117 | 2012 |
Synergistic solubilization of porcine myosin in physiological salt solution by arginine E Takai, S Yoshizawa, D Ejima, T Arakawa, K Shiraki International journal of biological macromolecules 62, 647-651, 2013 | 102 | 2013 |
Arginine-assisted solubilization system for drug substances: solubility experiment and simulation A Hirano, T Kameda, T Arakawa, K Shiraki The Journal of Physical Chemistry B 114 (42), 13455-13462, 2010 | 102 | 2010 |
Viscosity control of protein solution by small solutes: a review T Hong, K Iwashita, K Shiraki Current Protein and Peptide Science 19 (8), 746-758, 2018 | 101 | 2018 |
A new class of glutathione S-transferase from the hepatopancreas of the red sea bream Pagrus major T Konishi, K Kato, T Araki, K Shiraki, M Takagi, Y Tamaru Biochemical Journal 388 (1), 299-307, 2005 | 100 | 2005 |
Arginine ethylester prevents thermal inactivation and aggregation of lysozyme K Shiraki, M Kudou, S Nishikori, H Kitagawa, T Imanaka, M Takagi European journal of biochemistry 271 (15), 3242-3247, 2004 | 98 | 2004 |
Discovery of posttranslational maturation by self-subunit swapping Z Zhou, Y Hashimoto, K Shiraki, M Kobayashi Proceedings of the National Academy of Sciences 105 (39), 14849-14854, 2008 | 97 | 2008 |
Characterization of phytochelatin synthase-like protein encoded by alr0975 from a prokaryote, Nostoc sp. PCC 7120 N Tsuji, S Nishikori, O Iwabe, K Shiraki, H Miyasaka, M Takagi, K Hirata, ... Biochemical and Biophysical Research Communications 315 (3), 751-755, 2004 | 91 | 2004 |
Arginine increases the solubility of coumarin: comparison with salting-in and salting-out additives A Hirano, T Arakawa, K Shiraki Journal of biochemistry 144 (3), 363-369, 2008 | 88 | 2008 |
Effects of alcohol on the solubility and structure of native and disulfide-modified bovine serum albumin H Yoshikawa, A Hirano, T Arakawa, K Shiraki International journal of biological macromolecules 50 (5), 1286-1291, 2012 | 85 | 2012 |
High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine L Ito, K Shiraki, T Matsuura, M Okumura, K Hasegawa, S Baba, ... Protein Engineering, Design & Selection 24 (3), 269-274, 2011 | 82 | 2011 |
L-argininamide improves the refolding more effectively than L-arginine H Hamada, K Shiraki Journal of biotechnology 130 (2), 153-160, 2007 | 78 | 2007 |
Arginine and lysine reduce the high viscosity of serum albumin solutions for pharmaceutical injection N Inoue, E Takai, T Arakawa, K Shiraki Journal of bioscience and bioengineering 117 (5), 539-543, 2014 | 74 | 2014 |