| Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ... Nature genetics 49 (12), 1779-1784, 2017 | 1404 | 2017 |
| Spiroindolones, a potent compound class for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... science 329 (5996), 1175-1180, 2010 | 1191 | 2010 |
| Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ... Science 334 (6061), 1372-1377, 2011 | 350 | 2011 |
| Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families SER Bopp, MJ Manary, AT Bright, GL Johnston, NV Dharia, FL Luna, ... PLoS genetics 9 (2), e1003293, 2013 | 227 | 2013 |
| Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ... Nature genetics 50 (9), 1240-1246, 2018 | 201 | 2018 |
| Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum NV Dharia, ABS Sidhu, MB Cassera, SJ Westenberger, SER Bopp, ... Genome biology 10 (2), 1-13, 2009 | 154 | 2009 |
| Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites RT Eastman, NV Dharia, EA Winzeler, DA Fidock Antimicrobial agents and chemotherapy 55 (8), 3908-3916, 2011 | 152 | 2011 |
| Validation of isoleucine utilization targets in Plasmodium falciparum ES Istvan, NV Dharia, SE Bopp, I Gluzman, EA Winzeler, DE Goldberg Proceedings of the National Academy of Sciences 108 (4), 1627-1632, 2011 | 142 | 2011 |
| CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2 L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ... The Journal of clinical investigation 128 (1), 446-462, 2018 | 128 | 2018 |
| A Systems-Based Analysis of Plasmodium vivax Lifecycle Transcription from Human to Mosquito SJ Westenberger, CM McClean, R Chattopadhyay, NV Dharia, JM Carlton, ... PLoS neglected tropical diseases 4 (4), e653, 2010 | 128 | 2010 |
| EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma AB Iniguez, B Stolte, EJ Wang, AS Conway, G Alexe, NV Dharia, ... Cancer cell 33 (2), 202-216. e6, 2018 | 126 | 2018 |
| Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes NV Dharia, AT Bright, SJ Westenberger, SW Barnes, S Batalov, K Kuhen, ... Proceedings of the National Academy of Sciences 107 (46), 20045-20050, 2010 | 122 | 2010 |
| A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor T Nam, CW McNamara, S Bopp, NV Dharia, S Meister, GMC Bonamy, ... ACS chemical biology 6 (11), 1214-1222, 2011 | 102 | 2011 |
| Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core … SJ Westenberger, L Cui, N Dharia, E Winzeler, L Cui BMC genomics 10, 1-17, 2009 | 95 | 2009 |
| Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ... Nature communications 9 (1), 2024, 2018 | 89 | 2018 |
| A first-generation pediatric cancer dependency map NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ... Nature genetics 53 (4), 529-538, 2021 | 73 | 2021 |
| Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites NV Dharia, D Plouffe, SER Bopp, GE González-Páez, C Lucas, C Salas, ... Genome research 20 (11), 1534-1544, 2010 | 72 | 2010 |
| Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia Y Gocho, J Liu, J Hu, W Yang, NV Dharia, J Zhang, H Shi, G Du, A John, ... Nature cancer 2 (3), 284-299, 2021 | 71 | 2021 |
| A combination CDK4/6 and IGF1R inhibitor strategy for Ewing sarcoma LM Guenther, NV Dharia, L Ross, A Conway, AL Robichaud, JL Catlett, ... Clinical Cancer Research 25 (4), 1343-1357, 2019 | 70 | 2019 |
| Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma B Stolte, AB Iniguez, NV Dharia, AL Robichaud, AS Conway, AM Morgan, ... Journal of Experimental Medicine 215 (8), 2137-2155, 2018 | 63 | 2018 |
