Follow
Neekesh V. Dharia
Title
Cited by
Cited by
Year
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ...
Nature genetics 49 (12), 1779-1784, 2017
11812017
Spiroindolones, a potent compound class for the treatment of malaria
M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ...
science 329 (5996), 1175-1180, 2010
11112010
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery
S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ...
Science 334 (6061), 1372-1377, 2011
3332011
Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families
SER Bopp, MJ Manary, AT Bright, GL Johnston, NV Dharia, FL Luna, ...
PLoS genetics 9 (2), e1003293, 2013
2062013
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum
NV Dharia, ABS Sidhu, MB Cassera, SJ Westenberger, SER Bopp, ...
Genome biology 10 (2), 1-13, 2009
1542009
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ...
Nature genetics 50 (9), 1240-1246, 2018
1532018
Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites
RT Eastman, NV Dharia, EA Winzeler, DA Fidock
Antimicrobial agents and chemotherapy 55 (8), 3908-3916, 2011
1452011
Validation of isoleucine utilization targets in Plasmodium falciparum
ES Istvan, NV Dharia, SE Bopp, I Gluzman, EA Winzeler, DE Goldberg
Proceedings of the National Academy of Sciences 108 (4), 1627-1632, 2011
1312011
A Systems-Based Analysis of Plasmodium vivax Lifecycle Transcription from Human to Mosquito
SJ Westenberger, CM McClean, R Chattopadhyay, NV Dharia, JM Carlton, ...
PLoS neglected tropical diseases 4 (4), e653, 2010
1242010
Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes
NV Dharia, AT Bright, SJ Westenberger, SW Barnes, S Batalov, K Kuhen, ...
Proceedings of the National Academy of Sciences 107 (46), 20045-20050, 2010
1182010
EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma
AB Iniguez, B Stolte, EJ Wang, AS Conway, G Alexe, NV Dharia, ...
Cancer cell 33 (2), 202-216. e6, 2018
1062018
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2
L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ...
The Journal of clinical investigation 128 (1), 446-462, 2018
1062018
A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor
T Nam, CW McNamara, S Bopp, NV Dharia, S Meister, GMC Bonamy, ...
ACS chemical biology 6 (11), 1214-1222, 2011
962011
Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core …
SJ Westenberger, L Cui, N Dharia, E Winzeler, L Cui
BMC genomics 10, 1-17, 2009
902009
Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models
SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ...
Nature communications 9 (1), 2024, 2018
792018
Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites
NV Dharia, D Plouffe, SER Bopp, GE González-Páez, C Lucas, C Salas, ...
Genome research 20 (11), 1534-1544, 2010
712010
A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing SarcomaCDK4/6 and IGF1R Inhibitors Are Synergistic in Ewing Sarcoma
LM Guenther, NV Dharia, L Ross, A Conway, AL Robichaud, JL Catlett, ...
Clinical Cancer Research 25 (4), 1343-1357, 2019
562019
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma
B Stolte, AB Iniguez, NV Dharia, AL Robichaud, AS Conway, AM Morgan, ...
Journal of Experimental Medicine 215 (8), 2137-2155, 2018
552018
A first-generation pediatric cancer dependency map
NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ...
Nature genetics 53 (4), 529-538, 2021
502021
Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia
Y Gocho, J Liu, J Hu, W Yang, NV Dharia, J Zhang, H Shi, G Du, A John, ...
Nature cancer 2 (3), 284-299, 2021
482021
The system can't perform the operation now. Try again later.
Articles 1–20