Neekesh V. Dharia
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Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ...
Nature genetics 49 (12), 1779-1784, 2017
Spiroindolones, a potent compound class for the treatment of malaria
M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ...
science 329 (5996), 1175-1180, 2010
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery
S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ...
Science 334 (6061), 1372-1377, 2011
Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families
SER Bopp, MJ Manary, AT Bright, GL Johnston, NV Dharia, FL Luna, ...
PLoS genetics 9 (2), e1003293, 2013
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ...
Nature genetics 50 (9), 1240-1246, 2018
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum
NV Dharia, ABS Sidhu, MB Cassera, SJ Westenberger, SER Bopp, ...
Genome biology 10 (2), 1-13, 2009
Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites
RT Eastman, NV Dharia, EA Winzeler, DA Fidock
Antimicrobial agents and chemotherapy 55 (8), 3908-3916, 2011
Validation of isoleucine utilization targets in Plasmodium falciparum
ES Istvan, NV Dharia, SE Bopp, I Gluzman, EA Winzeler, DE Goldberg
Proceedings of the National Academy of Sciences 108 (4), 1627-1632, 2011
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2
L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ...
The Journal of clinical investigation 128 (1), 446-462, 2018
A Systems-Based Analysis of Plasmodium vivax Lifecycle Transcription from Human to Mosquito
SJ Westenberger, CM McClean, R Chattopadhyay, NV Dharia, JM Carlton, ...
PLoS neglected tropical diseases 4 (4), e653, 2010
EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma
AB Iniguez, B Stolte, EJ Wang, AS Conway, G Alexe, NV Dharia, ...
Cancer cell 33 (2), 202-216. e6, 2018
Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes
NV Dharia, AT Bright, SJ Westenberger, SW Barnes, S Batalov, K Kuhen, ...
Proceedings of the National Academy of Sciences 107 (46), 20045-20050, 2010
A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor
T Nam, CW McNamara, S Bopp, NV Dharia, S Meister, GMC Bonamy, ...
ACS chemical biology 6 (11), 1214-1222, 2011
Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core …
SJ Westenberger, L Cui, N Dharia, E Winzeler, L Cui
BMC genomics 10, 1-17, 2009
Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models
SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ...
Nature communications 9 (1), 2024, 2018
A first-generation pediatric cancer dependency map
NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ...
Nature genetics 53 (4), 529-538, 2021
Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites
NV Dharia, D Plouffe, SER Bopp, GE González-Páez, C Lucas, C Salas, ...
Genome research 20 (11), 1534-1544, 2010
Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia
Y Gocho, J Liu, J Hu, W Yang, NV Dharia, J Zhang, H Shi, G Du, A John, ...
Nature cancer 2 (3), 284-299, 2021
A combination CDK4/6 and IGF1R inhibitor strategy for Ewing sarcoma
LM Guenther, NV Dharia, L Ross, A Conway, AL Robichaud, JL Catlett, ...
Clinical Cancer Research 25 (4), 1343-1357, 2019
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma
B Stolte, AB Iniguez, NV Dharia, AL Robichaud, AS Conway, AM Morgan, ...
Journal of Experimental Medicine 215 (8), 2137-2155, 2018
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