Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy SS Seregin, DM Appledorn, AJ McBride, NJ Schuldt, YA Aldhamen, ... Molecular Therapy 17 (4), 685-696, 2009 | 114 | 2009 |
Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis DP Zachs, SJ Offutt, RS Graham, Y Kim, J Mueller, JL Auger, NJ Schuldt, ... Nature communications 10 (1), 951, 2019 | 107 | 2019 |
Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors DM Appledorn, A McBride, S Seregin, JM Scott, N Schuldt, A Kiang, ... Gene therapy 15 (24), 1606-1617, 2008 | 90 | 2008 |
Dual TCR T cells: identity crisis or multitaskers? NJ Schuldt, BA Binstadt The Journal of Immunology 202 (3), 637-644, 2019 | 67 | 2019 |
Malaria vaccines: focus on adenovirus based vectors NJ Schuldt, A Amalfitano Vaccine 30 (35), 5191-5198, 2012 | 47 | 2012 |
Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector–triggered immune responses in vitro and in vivo SS Seregin, YA Aldhamen, DM Appledorn, ZC Hartman, NJ Schuldt, ... Blood, The Journal of the American Society of Hematology 116 (10), 1669-1677, 2010 | 47 | 2010 |
A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target DM Appledorn, YA Aldhamen, W DePas, SS Seregin, CJJ Liu, N Schuldt, ... PLoS One 5 (3), e9579, 2010 | 43 | 2010 |
Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens YA Aldhamen, DM Appledorn, SS Seregin, CJ Liu, NJ Schuldt, ... The Journal of Immunology 186 (2), 722-732, 2011 | 42 | 2011 |
Cutting edge: Dual TCRα expression poses an autoimmune hazard by limiting regulatory T cell generation NJ Schuldt, JL Auger, JA Spanier, T Martinov, ER Breed, BT Fife, ... The Journal of Immunology 199 (1), 33-38, 2017 | 29 | 2017 |
CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies SS Seregin, YA Aldhamen, DM Appledorn, NJ Schuldt, AJ McBride, ... Gene therapy 16 (10), 1245-1259, 2009 | 25 | 2009 |
Vaccines expressing the innate immune modulator EAT-2 elicit potent effector memory T lymphocyte responses despite pre-existing vaccine immunity YA Aldhamen, SS Seregin, NJ Schuldt, DPW Rastall, CJ Liu, ... The Journal of Immunology 189 (3), 1349-1359, 2012 | 19 | 2012 |
Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses NJ Schuldt, YA Aldhamen, DM Appledorn, SS Seregin, Y Kousa, ... PLoS One 6 (8), e24147, 2011 | 17 | 2011 |
Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and adenovirus (Ad5) immune mice NJ Schuldt, YA Aldhamen, S Godbehere-Roosa, SS Seregin, YA Kousa, ... Malaria Journal 11, 1-14, 2012 | 15 | 2012 |
Bi-allelic TCRα or β recombination enhances T cell development but is dispensable for antigen responses and experimental autoimmune encephalomyelitis NJ Schuldt, JL Auger, KA Hogquist, BA Binstadt Plos one 10 (12), e0145762, 2015 | 7 | 2015 |
Natural Microbial Exposure from the Earliest Natural Time Point Enhances Immune Development by Expanding Immune Cell Progenitors and Mature Immune Cells S Burger, T Stenger, M Pierson, A Sridhar, MA Huggins, TA Kucaba, ... The Journal of Immunology 210 (11), 1740-1751, 2023 | 6 | 2023 |
Normal microbial experiences accelerate memory T cell compartment maturation in infants TD Stenger, S Burger, M Pierson, M Huggins, S Hamilton, NJ Schuldt The Journal of Immunology 208 (1_Supplement), 57.09-57.09, 2022 | | 2022 |
Exposure to diverse microbial flora accelerates the development of infant immunity NJ Schuldt, S Burger, T Stenger, M Pierson, M Huggins The Journal of Immunology 208 (1_Supplement), 170.07-170.07, 2022 | | 2022 |
Dual TCRα expression alters agonist selection, redirecting Treg-biased insulin-specific thymocytes into the conventional T cell lineage NJ Schuldt, JL Auger, J Spanier, T Martinov, ER Breed, BT Fife, ... The Journal of Immunology 198 (1_Supplement), 156.4-156.4, 2017 | | 2017 |
Absence of dual TCR T cells protects NOD mice from diabetes due to an increased insulin-specific Treg: Teff ratio NJ Schuldt, JA Spanier, JL Auger, KA Hogquist, BT Fife, BA Binstadt The Journal of Immunology 196 (1_Supplement), 186.21-186.21, 2016 | | 2016 |
Biallelic T cell receptor rearrangement enhances the efficiency of thymocyte development and positive selection.(HEM4P. 234) N Schuldt, J Auger, K Hogquist, B Binstadt The Journal of Immunology 192 (1_Supplement), 116.10-116.10, 2014 | | 2014 |