Hugo Menzella
Hugo Menzella
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Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes
HG Menzella, R Reid, JR Carney, SS Chandran, SJ Reisinger, KG Patel, ...
Nature biotechnology 23 (9), 1171-1176, 2005
Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster
SJ Kodumal, KG Patel, R Reid, HG Menzella, M Welch, DV Santi
Proceedings of the National Academy of Sciences 101 (44), 15573-15578, 2004
Comparison of two codon optimization strategies to enhance recombinant protein production in Escherichia coli
HG Menzella
Microbial cell factories 10, 1-8, 2011
Combinatorial biosynthesis for drug development
HG Menzella, CD Reeves
Current opinion in microbiology 10 (3), 238-245, 2007
Expression of codon optimized genes in microbial systems: current industrial applications and perspectives
C Elena, P Ravasi, ME Castelli, S Peirú, HG Menzella
Frontiers in microbiology 5, 21, 2014
Production of the Potent Antibacterial Polyketide Erythromycin C in Escherichia coli
S Peirú, HG Menzella, E Rodriguez, J Carney, H Gramajo
Applied and environmental microbiology 71 (5), 2539-2547, 2005
Rational design and assembly of synthetic trimodular polyketide synthases
HG Menzella, JR Carney, DV Santi
Chemistry & biology 14 (2), 143-151, 2007
The antifungal polyketide ambruticin targets the HOG pathway
LK Leandro Vetcher, Hugo G Menzella, Toshiaki Kudo, Takayuki Motoyama
Antimicrob. Agents Chemother 51 (10), 3734-3736, 2007
Novel Escherichia coli strain allows efficient recombinant protein production using lactose as inducer
HG Menzella, EA Ceccarelli, HC Gramajo
Biotechnology and bioengineering 82 (7), 809-817, 2003
Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster
HG Menzella, SJ Reisinger, M Welch, JT Kealey, J Kennedy, R Reid, ...
Journal of Industrial Microbiology and Biotechnology 33 (1), 22-28, 2006
High recovery of prochymosin from inclusion bodies using controlled air oxidation
HG Menzella, HC Gramajo, EA Ceccarelli
Protein expression and purification 25 (2), 248-255, 2002
Industrial uses of phospholipases: current state and future applications
S Cerminati, L Paoletti, A Aguirre, S Peirú, HG Menzella, ME Castelli
Applied microbiology and biotechnology 103 (6), 2571-2582, 2019
Design and testing of a synthetic biology framework for genetic engineering of Corynebacterium glutamicum
P Ravasi, S Peiru, H Gramajo, HG Menzella
Microbial cell factories 11, 1-11, 2012
Activating hybrid modular interfaces in synthetic polyketide synthases by cassette replacement of ketosynthase domains
SS Chandran, HG Menzella, JR Carney, DV Santi
Chemistry & biology 13 (5), 469-474, 2006
Enzymatic hydrolysis of steryl glucosides, major contaminants of vegetable oil-derived biodiesel
A Aguirre, S Peiru, F Eberhardt, L Vetcher, R Cabrera, HG Menzella
Applied microbiology and biotechnology 98, 4033-4040, 2014
Potent Non-Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors from Genetic Engineering of Streptomyces hygroscopicus
HG Menzella, TT Tran, JR Carney, J Lau-Wee, J Galazzo, CD Reeves, ...
Journal of medicinal chemistry 52 (6), 1518-1521, 2009
Heterologous production of polyketides in bacteria
E Rodriguez, HG Menzella, H Gramajo
Methods in enzymology 459, 339-365, 2009
High-level production of Bacillus cereus phospholipase C in Corynebacterium glutamicum
P Ravasi, M Braia, F Eberhardt, C Elena, S Cerminati, S Peirú, ...
Journal of Biotechnology 216, 142-148, 2015
Low cost and sustainable hyaluronic acid production in a manufacturing platform based on Bacillus subtilis 3NA strain
S Cerminati, M Leroux, P Anselmi, S Peirú, JC Alonso, B Priem, ...
Applied Microbiology and Biotechnology 105, 3075-3086, 2021
Metabolically engineered Escherichia coli for efficient production of glycosylated natural products
S Peirú, E Rodríguez, HG Menzella, JR Carney, H Gramajo
Microbial biotechnology 1 (6), 476-486, 2008
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