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Xue Wu
Xue Wu
Geneseeq Technology Inc.
Verified email at geneseeq.com
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Year
Investigating novel resistance mechanisms to third-generation EGFR tyrosine kinase inhibitor osimertinib in non–small cell lung cancer patients
Z Yang, N Yang, Q Ou, Y Xiang, T Jiang, X Wu, H Bao, X Tong, X Wang, ...
Clinical Cancer Research 24 (13), 3097-3107, 2018
4082018
Widespread and functional RNA circularization in localized prostate cancer
S Chen, V Huang, X Xu, J Livingstone, F Soares, J Jeon, Y Zeng, JT Hua, ...
Cell 176 (4), 831-843. e22, 2019
3432019
Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome–associated PTPN11 mutation
TM Marin, K Keith, B Davies, DA Conner, P Guha, D Kalaitzidis, X Wu, ...
The Journal of clinical investigation 121 (3), 1026-1043, 2011
2892011
MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1L613V mutation
X Wu, J Simpson, JH Hong, KH Kim, NK Thavarajah, PH Backx, BG Neel, ...
The Journal of clinical investigation 121 (3), 1009-1025, 2011
2282011
Circulating tumor DNA mutation profiling by targeted next generation sequencing provides guidance for personalized treatments in multiple cancer types
Y Shu, X Wu, X Tong, X Wang, Z Chang, Y Mao, X Chen, J Sun, Z Wang, ...
Scientific reports 7 (1), 583, 2017
1832017
Comprehensive genomic profiling identifies novel genetic predictors of response to anti–PD-(L) 1 therapies in non–small cell lung cancer
W Fang, Y Ma, JC Yin, S Hong, H Zhou, A Wang, F Wang, H Bao, X Wu, ...
Clinical Cancer Research 25 (16), 5015-5026, 2019
1522019
Liquid biopsies to track trastuzumab resistance in metastatic HER2-positive gastric cancer
DS Wang, ZX Liu, YX Lu, H Bao, X Wu, ZL Zeng, Z Liu, Q Zhao, CY He, ...
Gut 68 (7), 1152-1161, 2019
1472019
Correlation of plasma exosomal microRNAs with the efficacy of immunotherapy in EGFR/ALK wild-type advanced non-small cell lung cancer
XX Peng, R Yu, X Wu, SY Wu, C Pi, ZH Chen, XC Zhang, CY Gao, ...
Journal for Immunotherapy of Cancer 8 (1), 2020
1392020
Novel mutations on EGFR Leu792 potentially correlate to acquired resistance to osimertinib in advanced NSCLC
K Chen, F Zhou, W Shen, T Jiang, X Wu, X Tong, YW Shao, S Qin, C Zhou
Journal of Thoracic Oncology 12 (6), e65-e68, 2017
952017
Genes associated with increased brain metastasis risk in non–small cell lung cancer: Comprehensive genomic profiling of 61 resected brain metastases versus primary non–small …
H Wang, Q Ou, D Li, T Qin, H Bao, X Hou, K Wang, F Wang, Q Deng, ...
Cancer 125 (20), 3535-3544, 2019
942019
Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer
SD Bailey, K Desai, KJ Kron, P Mazrooei, NA Sinnott-Armstrong, ...
Nature genetics 48 (10), 1260-1266, 2016
942016
Tumor-derived DNA from pleural effusion supernatant as a promising alternative to tumor tissue in genomic profiling of advanced lung cancer
L Tong, N Ding, X Tong, J Li, Y Zhang, X Wang, X Xu, M Ye, C Li, X Wu, ...
Theranostics 9 (19), 5532, 2019
892019
Utility of ctDNA in predicting response to neoadjuvant chemoradiotherapy and prognosis assessment in locally advanced rectal cancer: A prospective cohort study
Y Wang, L Yang, H Bao, X Fan, F Xia, J Wan, L Shen, Y Guan, H Bao, ...
PLoS Medicine 18 (8), e1003741, 2021
752021
Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells
BH Yoo, X Wu, Y Li, M Haniff, T Sasazuki, S Shirasawa, EL Eskelinen, ...
Journal of biological chemistry 285 (8), 5438-5449, 2010
652010
Acquired EGFR L718V mutation mediates resistance to osimertinib in non-small cell lung cancer but retains sensitivity to afatinib
Y Liu, Y Li, Q Ou, X Wu, X Wang, YW Shao, J Ying
Lung Cancer 118, 1-5, 2018
642018
Detachment-induced upregulation of XIAP and cIAP2 delays anoikis of intestinal epithelial cells
Z Liu, H Li, X Wu, BH Yoo, SR Yan, AW Stadnyk, T Sasazuki, S Shirasawa, ...
Oncogene 25 (59), 7680-7690, 2006
622006
Genomic signatures define three subtypes of EGFR-mutant stage II–III non-small-cell lung cancer with distinct adjuvant therapy outcomes
SY Liu, H Bao, Q Wang, WM Mao, Y Chen, X Tong, ST Xu, L Wu, YC Wei, ...
Nature communications 12 (1), 6450, 2021
592021
Adipocyte Enhancer‐Binding Protein 1 Modulates Adiposity and Energy Homeostasis
HS Ro, L Zhang, A Majdalawieh, SW Kim, X Wu, PJ Lyons, C Webber, ...
Obesity 15 (2), 288-302, 2012
572012
Evidence of NTRK1 fusion as resistance mechanism to EGFR TKI in EGFR+ NSCLC: results from a large-scale survey of NTRK1 fusions in Chinese patients with lung cancer
H Xia, X Xue, H Ding, Q Ou, X Wu, M Nagasaka, YW Shao, X Hu, SHI Ou
Clinical lung cancer 21 (3), 247-254, 2020
562020
Increased BRAF heterodimerization is the common pathogenic mechanism for Noonan Syndrome-associated RAF1 mutants
X Wu, J Yin, J Simpson, KH Kim, S Gu, JH Hong, P Bayliss, PH Backx, ...
Molecular and Cellular Biology 32 (19), 3872-3890, 2012
532012
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