Michael H. Gelb
Michael H. Gelb
Professor of Chemistry, University of Washington
Verified email at - Homepage
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Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
SP Gygi, B Rist, SA Gerber, F Turecek, MH Gelb, R Aebersold
Nature biotechnology 17 (10), 994-999, 1999
Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction
JB Siegel, A Zanghellini, HM Lovick, G Kiss, AR Lambert, JL St. Clair, ...
Science 329 (5989), 309-313, 2010
Interfacial catalysis: the mechanism of phospholipase A2
DL Scott, SP White, Z Otwinowski, W Yuan, MH Gelb, PB Sigler
Science 250 (4987), 1541-1546, 1990
Biochemistry and physiology of mammalian secreted phospholipases A2
G Lambeau, MH Gelb
Annual review of biochemistry 77 (1), 495-520, 2008
Prenyl proteins in eukaryotic cells: a new type of membrane anchor
JA Glomset, MH Gelb, CC Farnsworth
Trends in biochemical sciences 15 (4), 139-142, 1990
Slow-and tight-binding inhibitors of the 85-kDa human phospholipase A2
IP Street, HK Lin, F Laliberte, F Ghomashchi, Z Wang, H Perrier, ...
Biochemistry 32 (23), 5935-5940, 1993
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation
LH Boudreau, AC Duchez, N Cloutier, D Soulet, N Martin, J Bollinger, ...
Blood, The Journal of the American Society of Hematology 124 (14), 2173-2183, 2014
Fluoro ketone inhibitors of hydrolytic enzymes
MH Gelb, JP Svaren, RH Abeles
Biochemistry 24 (8), 1813-1817, 1985
Interfacial Enzymology:  The Secreted Phospholipase A2-Paradigm
OG Berg, MH Gelb, MD Tsai, MK Jain
Chemical reviews 101 (9), 2613-2654, 2001
Translocation of the 85-kDa Phospholipase A2 from Cytosol to the Nuclear Envelope in Rat Basophilic Leukemia Cells Stimulated with Calcium Ionophore or IgE/Antigen (∗)
S Glover, T Bayburt, M Jonas, E Chi, MH Gelb
Journal of Biological Chemistry 270 (25), 15359-15367, 1995
Crystal Structure of Bee-Venom Phospholipase A2 in a Complex with a Transition-State Analogue
DL Scott, Z Otwinowski, MH Gelb, PB Sigler
Science 250 (4987), 1563-1566, 1990
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
RL Wilensky, YI Shi, ER Mohler, D Hamamdzic, ME Burgert, J Li, A Postle, ...
Nature medicine 14 (10), 1059-1066, 2008
Direct multiplex assay of lysosomal enzymes in dried blood spots for newborn screening
Y Li, CR Scott, NA Chamoles, A Ghavami, BM Pinto, F Turecek, MH Gelb
Clinical chemistry 50 (10), 1785-1796, 2004
Human lamin B contains a farnesylated cysteine residue
CC Farnsworth, SL Wolda, MH Gelb, JA Glomset
Journal of Biological Chemistry 264 (34), 20422-20429, 1989
Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2
AG Singer, F Ghomashchi, C Le Calvez, J Bollinger, S Bezzine, ...
Journal of Biological Chemistry 277 (50), 48535-48549, 2002
Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue
SP White, DL Scott, Z Otwinowski, MH Gelb, PB Sigler
Science 250 (4987), 1560-1563, 1990
Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson–Gilford progeria syndrome mutation
SH Yang, MO Bergo, JI Toth, X Qiao, Y Hu, S Sandoval, M Meta, ...
Proceedings of the National Academy of Sciences 102 (29), 10291-10296, 2005
Structures of free and inhibited human secretory phospholipase A2 from inflammatory exudate
DL Scott, SP White, JL Browning, JJ Rosa, MH Gelb, PB Sigler
Science 254 (5034), 1007-1010, 1991
Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini.
HK Yamane, CC Farnsworth, HY Xie, W Howald, BK Fung, S Clarke, ...
Proceedings of the National Academy of Sciences 87 (15), 5868-5872, 1990
Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes
JI Toth, SH Yang, X Qiao, AP Beigneux, MH Gelb, CL Moulson, JH Miner, ...
Proceedings of the National Academy of Sciences 102 (36), 12873-12878, 2005
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