| Integrated genomic characterization of pancreatic ductal adenocarcinoma BJ Raphael, RH Hruban, AJ Aguirre, RA Moffitt, JJ Yeh, C Stewart, ... Cancer cell 32 (2), 185-203. e13, 2017 | 1039 | 2017 |
| Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes B Chapuy, C Stewart, AJ Dunford, J Kim, A Kamburov, RA Redd, ... Nature medicine 24 (5), 679-690, 2018 | 893 | 2018 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 862 | 2020 |
| Resistance to checkpoint blockade therapy through inactivation of antigen presentation M Sade-Feldman, YJ Jiao, JH Chen, MS Rooney, M Barzily-Rokni, ... Nature communications 8 (1), 1-11, 2017 | 527 | 2017 |
| The evolutionary history of 2,658 cancers M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ... Nature 578 (7793), 122-128, 2020 | 505 | 2020 |
| Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ... Nature communications 8 (1), 1-13, 2017 | 447 | 2017 |
| A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer P Polak, J Kim, LZ Braunstein, R Karlic, NJ Haradhavala, G Tiao, ... Nature genetics 49 (10), 1476-1486, 2017 | 356 | 2017 |
| RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues K Yizhak, F Aguet, J Kim, JM Hess, K Kübler, J Grimsby, R Frazer, ... Science 364 (6444), eaaw0726, 2019 | 307 | 2019 |
| Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers AR Parikh, I Leshchiner, L Elagina, L Goyal, C Levovitz, G Siravegna, ... Nature medicine 25 (9), 1415-1421, 2019 | 218 | 2019 |
| Mitochondrial reprogramming underlies resistance to BCL-2 inhibition in lymphoid malignancies R Guièze, VM Liu, D Rosebrock, AA Jourdain, M Hernández-Sánchez, ... Cancer cell 36 (4), 369-384. e13, 2019 | 154 | 2019 |
| The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy DA Landau, C Sun, D Rosebrock, SEM Herman, J Fein, M Sivina, ... Nature communications 8 (1), 1-12, 2017 | 136 | 2017 |
| Pan-cancer analysis of whole genomes. S Hirano, L Yang, M Juul, CA Purdie, BP O'Neill, R Kabbe, ... Nature 578 (DKFZ-2020-01051), 82-93, 2020 | 132 | 2020 |
| Widespread chromosomal losses and mitochondrial DNA alterations as genetic drivers in Hürthle cell carcinoma RK Gopal, K Kübler, SE Calvo, P Polak, D Livitz, D Rosebrock, PM Sadow, ... Cancer Cell 34 (2), 242-255. e5, 2018 | 127 | 2018 |
| Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair NJ Haradhvala, J Kim, YE Maruvka, P Polak, D Rosebrock, D Livitz, ... Nature communications 9 (1), 1-9, 2018 | 115 | 2018 |
| Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... Cell 184 (8), 2239-2254. e39, 2021 | 96 | 2021 |
| Growth dynamics in naturally progressing chronic lymphocytic leukaemia M Gruber, I Bozic, I Leshchiner, D Livitz, K Stevenson, L Rassenti, ... Nature 570 (7762), 474-479, 2019 | 67 | 2019 |
| Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... BioRxiv, 312041, 2018 | 47* | 2018 |
| Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment I Leshchiner, D Livitz, JF Gainor, D Rosebrock, O Spiro, A Martinez, ... biorxiv, 508127, 2019 | 30 | 2019 |
| FireCloud, a scalable cloud-based platform for collaborative genome analysis: strategies for reducing and controlling costs C Birger, M Hanna, E Salinas, J Neff, G Saksena, D Livitz, D Rosebrock, ... bioRxiv, 209494, 2017 | 28 | 2017 |
| Resolving the phylogenetic origin of glioblastoma via multifocal genomic analysis of pre-treatment and treatment-resistant autopsy specimens PK Brastianos, N Nayyar, D Rosebrock, I Leshchiner, CM Gill, D Livitz, ... NPJ precision oncology 1 (1), 1-8, 2017 | 24 | 2017 |
Daniel RosebrockBroad InstituteVerified email at broadinstitute.org
