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Jean A. Bernatchez
Jean A. Bernatchez
Senior Scientist and San Diego R&D Group Leader, Eurofins Discovery
Verified email at eurofinsUS.com
Title
Cited by
Cited by
Year
Cysteine proteases in protozoan parasites
JL Siqueira-Neto, A Debnath, LI McCall, JA Bernatchez, M Ndao, ...
PLoS Neglected Tropical Diseases 12 (8), e0006512, 2018
1542018
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ...
Cell Stem Cell 26 (2), 187-204, 2020
1372020
Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B
MH Powdrill, JA Bernatchez, M Götte
Viruses 2 (10), 2169-2195, 2010
1192010
Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy
Y Luan, J Li, JA Bernatchez, R Li
Journal of Medicinal Chemistry 62 (7), 3171-3183, 2019
1112019
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ...
Journal of Experimental Medicine 216 (5), 1071-1090, 2019
982019
Drugs for the Treatment of Zika Virus Infection
JA Bernatchez, LT Tran, J Li, Y Luan, JL Siqueira-Neto, R Li
Journal of Medicinal Chemistry 63 (2), 470-489, 2020
802020
Machine Learning Models Identify Inhibitors of SARS-CoV-2
VO Gawriljuk, PPK Zin, AC Puhl, KM Zorn, DH Foil, TR Lane, B Hurst, ...
Journal of Chemical Information and Modeling, 2021
422021
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies
BC Prager, HN Vasudevan, D Dixit, JA Bernatchez, Q Wu, LC Wallace, ...
Cancer Discovery 10, 1722–1741, 2020
422020
Mass spectrometry-based chemical cartography of a cardiac parasitic infection
LI McCall, JT Morton, JA Bernatchez, JL de Siqueira-Neto, R Knight, ...
Analytical chemistry 89 (19), 10414-10421, 2017
422017
Mechanism of action of methotrexate against Zika virus
S Beck, Z Zhu, MF Oliveira, DM Smith, JN Rich, JA Bernatchez, ...
Viruses 11 (4), 338, 2019
372019
Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics
J Balzarini, K Das, JA Bernatchez, SE Martinez, M Ngure, S Keane, ...
Proceedings of the National Academy of Sciences 112 (11), 3475-3480, 2015
372015
Dynamics of hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B in complex with RNA
P Karam, MH Powdrill, HW Liu, C Vasquez, W Mah, J Bernatchez, M Götte, ...
Journal of Biological Chemistry 289 (20), 14399-14411, 2014
342014
Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
Z Qiu, L Zhao, JZ Shen, Z Liang, Q Wu, K Yang, L Min, RC Gimple, ...
Cancer Discovery, 2021
312021
Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting Zika virus
JA Bernatchez, Z Yang, M Coste, J Li, S Beck, Y Liu, AE Clark, Z Zhu, ...
Antimicrobial agents and chemotherapy 62 (10), 10.1128/aac. 00725-18, 2018
262018
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases
L Li, BC Chenna, KS Yang, TR Cole, ZT Goodall, M Giardini, ...
Journal of Medicinal Chemistry, 2021
232021
Peptidomimetic Vinyl Heterocycle Inhibitors of Cruzain Effect Anti-Trypanosomal Activity
BC Chenna, L Li, DM Mellott, X Zhai, JL Siqueira-Neto, CM Calvet Alvarez, ...
Journal of Medicinal Chemistry 63 (6), 3298–3316, 2020
232020
Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors
B Singh, JA Bernatchez, LI McCall, CM Calvet, J Ackermann, JM Souza, ...
ACS Medicinal Chemistry Letters 11 (3), 249–257, 2020
172020
Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer
M Ehteshami, M Nijhuis, JA Bernatchez, CJ Ablenas, S McCormick, ...
Journal of Biological Chemistry 288 (24), 17336-17346, 2013
172013
Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase
JA Bernatchez, R Paul, EP Tchesnokov, M Ngure, GL Beilhartz, ...
Journal of Biological Chemistry 290 (3), 1474-1484, 2015
162015
Insights gained into respiratory infection pathogenesis using lung tissue metabolomics
JA Bernatchez, LI McCall
PLoS Pathogens 16 (7), e1008662, 2020
152020
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