Merja Heinäniemi
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Comprehensive Analysis of PPARα‐Dependent Regulation of Hepatic Lipid Metabolism by Expression Profiling
M Rakhshandehroo, LM Sanderson, M Matilainen, R Stienstra, ...
PPAR research 2007 (1), 026839, 2007
DICKKOPF-4 is induced by TCF/β-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1α, 25-dihydroxyvitamin D3
N Pendás-Franco, JM García, C Peña, N Valle, HG Pálmer, M Heinäniemi, ...
Oncogene 27 (32), 4467-4477, 2008
Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease
A Krishna, M Biryukov, C Trefois, PMA Antony, R Hussong, J Lin, ...
BMC genomics 15, 1-21, 2014
Role of the Keap1–Nrf2 pathway in cancer
HM Leinonen, E Kansanen, P Pölönen, M Heinäniemi, AL Levonen
Advances in cancer research 122, 281-320, 2014
Immunogenomic landscape of hematological malignancies
O Dufva, P Pölönen, O Brück, MAI Keränen, J Klievink, J Mehtonen, ...
Cancer Cell 38 (3), 380-399. e13, 2020
Gene-pair expression signatures reveal lineage control
M Heinäniemi, M Nykter, R Kramer, A Wienecke-Baldacchino, ...
Nature methods 10 (6), 577-583, 2013
Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis
DLM van der Meer, T Degenhardt, S Väisänen, PJ de Groot, ...
Nucleic acids research 38 (9), 2839-2850, 2010
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia
H Kuusanmäki, AM Leppä, P Pölönen, M Kontro, O Dufva, D Deb, ...
Haematologica 105 (3), 708, 2020
Regulation of multiple insulin-like growth factor binding protein genes by 1α,25-dihydroxyvitamin D3
M Matilainen, M Malinen, K Saavalainen, C Carlberg
Nucleic acids research 33 (17), 5521-5532, 2005
Meta-analysis of primary target genes of peroxisome proliferator-activated receptors
M Heinäniemi, JO Uski, T Degenhardt, C Carlberg
Genome biology 8, 1-29, 2007
HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development
CE de Bock, S Demeyer, S Degryse, D Verbeke, B Sweron, O Gielen, ...
Cancer discovery 8 (5), 616-631, 2018
Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators
F Molnár, M Matilainen, C Carlberg
Journal of Biological Chemistry 280 (28), 26543-26556, 2005
Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2
HK Jyrkkänen, S Kuosmanen, M Heinäniemi, H Laitinen, E Kansanen, ...
Biochemical Journal 440 (2), 167-174, 2011
Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis
C Frank, H Makkonen, TW Dunlop, M Matilainen, S Väisänen, C Carlberg
Journal of molecular biology 346 (2), 505-519, 2005
Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes
E John, A Wienecke-Baldacchino, M Liivrand, M Heinäniemi, C Carlberg, ...
Nucleic acids research 40 (10), 4446-4460, 2012
Dysregulation of the Keap1–Nrf2 pathway in cancer
HM Leinonen, E Kansanen, P Pölönen, M Heinäniemi, AL Levonen
Biochemical Society Transactions 43 (4), 645-649, 2015
The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors
T Degenhardt, M Matilainen, KH Herzig, TW Dunlop, C Carlberg
Journal of Biological Chemistry 281 (51), 39607-39619, 2006
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
P Pölönen, A Jawahar Deen, HM Leinonen, HK Jyrkkänen, S Kuosmanen, ...
Oncogene 38 (50), 7473-7490, 2019
Epigenetic control of a VDR-governed feed-forward loop that regulates p21 ( waf1/cip1 ) expression and function in …
JL Thorne, O Maguire, CL Doig, S Battaglia, L Fehr, LE Sucheston, ...
Nucleic acids research 39 (6), 2045-2056, 2011
Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network
M Galhardo, L Sinkkonen, P Berninger, J Lin, T Sauter, M Heinäniemi
Nucleic acids research 42 (3), 1474-1496, 2014
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