TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy CB Rodell, SP Arlauckas, MF Cuccarese, CS Garris, R Li, MS Ahmed, ... Nature biomedical engineering 2 (8), 578-588, 2018 | 807 | 2018 |
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 49 (6), 1148-1161. e7, 2018 | 770 | 2018 |
In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy SP Arlauckas, CS Garris, RH Kohler, M Kitaoka, MF Cuccarese, KS Yang, ... Science translational medicine 9 (389), eaal3604, 2017 | 588 | 2017 |
IRF3 and type I interferons fuel a fatal response to myocardial infarction KR King, AD Aguirre, YX Ye, Y Sun, JD Roh, RP Ng Jr, RH Kohler, ... Nature medicine 23 (12), 1481-1487, 2017 | 415 | 2017 |
Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages SP Arlauckas, SB Garren, CS Garris, RH Kohler, J Oh, MJ Pittet, ... Theranostics 8 (21), 5842, 2018 | 251 | 2018 |
Phase II trial of IL-12 plasmid transfection and PD-1 blockade in immunologically quiescent melanoma AP Algazi, CG Twitty, KK Tsai, M Le, R Pierce, E Browning, R Hermiz, ... Clinical Cancer Research 26 (12), 2827-2837, 2020 | 105 | 2020 |
Prediction of anti-cancer nanotherapy efficacy by imaging MA Miller, S Arlauckas, R Weissleder Nanotheranostics 1 (3), 296, 2017 | 73 | 2017 |
Recording the wild lives of immune cells MJ Pittet, CS Garris, SP Arlauckas, R Weissleder Science immunology 3 (27), eaaq0491, 2018 | 69 | 2018 |
Choline kinase alpha—Putting the ChoK-hold on tumor metabolism SP Arlauckas, AV Popov, EJ Delikatny Progress in Lipid Research 63, 28-40, 2016 | 67 | 2016 |
Quantification of tumor fluorescence during intraoperative optical cancer imaging RP Judy, JJ Keating, EM DeJesus, JX Jiang, OT Okusanya, S Nie, ... Scientific reports 5 (1), 16208, 2015 | 50 | 2015 |
Magnetic resonance spectroscopy for detection of choline kinase inhibition in the treatment of brain tumors M Kumar, SP Arlauckas, S Saksena, G Verma, R Ittyerah, S Pickup, ... Molecular cancer therapeutics 14 (4), 899-908, 2015 | 45 | 2015 |
Direct inhibition of choline kinase by a near-infrared fluorescent carbocyanine SP Arlauckas, AV Popov, EJ Delikatny Molecular cancer therapeutics 13 (9), 2149-2158, 2014 | 31 | 2014 |
Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors SP Arlauckas, M Kumar, AV Popov, H Poptani, EJ Delikatny Oncotarget 8 (10), 16518, 2017 | 27 | 2017 |
LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects HW Liao, C Garris, C Pfirschke, S Rickelt, S Arlauckas, M Siwicki, ... Cell Stress 3 (11), 348, 2019 | 23 | 2019 |
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 55 (9), 1749, 2022 | 12 | 2022 |
Imaging of cancer lipid metabolism in response to therapy SP Arlauckas, EA Browning, H Poptani, EJ Delikatny NMR in Biomedicine 32 (10), e4070, 2019 | 11 | 2019 |
Macrophage imaging and subset analysis using single-cell RNA sequencing S Arlauckas, N Oh, R Li, R Weissleder, MA Miller Nanotheranostics 5 (1), 36, 2021 | 7 | 2021 |
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-gamma and IL-12 (vol 49, 1148. e1, 2018) CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 55 (9), 1749-1749, 2022 | 2 | 2022 |
Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype B Sarkar, SP Arlauckas, MF Cuccarese, CS Garris, R Weissleder, ... Frontiers in Immunology 15, 1331480, 2024 | | 2024 |
Development of an ex vivo precision gene engineered B cell medicine that produces highly active and sustained levels of acid sphingomyelinase for the treatment of Neimann-Pick … M Musial-Siwek, I Datta, W Bainter, T Mullen, C Malloy, M Leiken, ... Molecular Genetics and Metabolism 141 (2), 107975, 2024 | | 2024 |