Walter Kolch
Walter Kolch
Director, Systems Biology Ireland, University College Dublin
Verified email at - Homepage
Cited by
Cited by
MAP kinase signalling pathways in cancer
AS Dhillon, S Hagan, O Rath, W Kolch
Oncogene 26 (22), 3279-3290, 2007
Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
W Kolch
Biochemical Journal 351 (2), 289-305, 2000
Protein kinase Cα activates RAF-1 by direct phosphorylation
W Kolch, G Heidecker, G Kochs, R Hummel, H Vahidi, H Mischak, ...
Nature 364 (6434), 249-252, 1993
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
W Kolch
Nature reviews Molecular cell biology 6 (11), 827-837, 2005
Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP
K Yeung, T Seitz, S Li, P Janosch, B McFerran, C Kaiser, F Fee, ...
Nature 401 (6749), 173-177, 1999
Signalling ballet in space and time
BN Kholodenko, JF Hancock, W Kolch
Nature reviews Molecular cell biology 11 (6), 414-426, 2010
Overexpression of protein kinase C-delta and-epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.
H Mischak, JA Goodnight, W Kolch, G Martiny-Baron, C Schaechtle, ...
Journal of Biological Chemistry 268 (9), 6090-6096, 1993
Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
A Kieser, HA Weich, G Brandner, D Marmé, W Kolch
Oncogene 9 (3), 963-970, 1994
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
W Kolch, G Heidecker, P Lloyd, UR Rapp
Nature 349 (6308), 426-428, 1991
Targeting MAPK signaling in cancer: mechanisms of drug resistance and sensitivity
S Lee, J Rauch, W Kolch
International journal of molecular sciences 21 (3), 1102, 2020
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity
CJ Gloeckner, N Kinkl, A Schumacher, RJ Braun, E O'Neill, T Meitinger, ...
Human molecular genetics 15 (2), 223-232, 2006
Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease
DM Good, P Zürbig, A Argiles, HW Bauer, G Behrens, JJ Coon, M Dakna, ...
Molecular & cellular proteomics 9 (11), 2424-2437, 2010
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway
RJ Orton, OE Sturm, V Vyshemirsky, M Calder, DR Gilbert, W Kolch
Biochemical Journal 392 (2), 249-261, 2005
Regulation and role of Raf-1/B-Raf heterodimerization
LK Rushworth, AD Hindley, E O'Neill, W Kolch
Molecular and cellular biology, 2006
Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein
K Yeung, P Janosch, B McFerran, DW Rose, H Mischak, JM Sedivy, ...
Molecular and cellular biology 20 (9), 3079-3085, 2000
Raf kinase inhibitor protein interacts with NF-κB-inducing kinase and TAK1 and inhibits NF-κB activation
KC Yeung, DW Rose, AS Dhillon, D Yaros, M Gustafsson, D Chatterjee, ...
Molecular and cellular biology 21 (21), 7207-7217, 2001
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells
S Kao, RK Jaiswal, W Kolch, GE Landreth
Journal of Biological Chemistry 276 (21), 18169-18177, 2001
Raf family kinases: old dogs have learned new tricks
D Matallanas, M Birtwistle, D Romano, A Zebisch, J Rauch, ...
Genes & cancer 2 (3), 232-260, 2011
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
D Matallanas, D Romano, K Yee, K Meissl, L Kucerova, D Piazzolla, ...
Molecular cell 27 (6), 962-975, 2007
Epstein–Barr virus latent membrane protein‐1 triggers AP‐1 activity via the c‐Jun N‐terminal kinase cascade
A Kieser, E Kilger, O Gires, M Ueffing, W Kolch, W Hammerschmidt
The EMBO journal, 1997
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