Francisco Saez-Orellana, PhD
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Synaptic failure and adenosine triphosphate imbalance induced by amyloid‐β aggregates are prevented by blueberry‐enriched polyphenols extract
J Fuentealba, AJ Dibarrart, MC Fuentes‐Fuentes, F Saez‐Orellana, ...
Journal of neuroscience research 89 (9), 1499-1508, 2011
ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxicity induced by soluble oligomers of β-amyloid peptide in hippocampal neurons
F Sáez-Orellana, PA Godoy, CY Bastidas, T Silva-Grecchi, L Guzmán, ...
Neuropharmacology 100, 116-123, 2016
Synaptic silencing and plasma membrane dyshomeostasis induced by amyloid-β peptide are prevented by Aristotelia chilensis enriched extract
J Fuentealba, A Dibarrart, F Saez-Orellana, MC Fuentes-Fuentes, ...
Journal of Alzheimer's Disease 31 (4), 879-889, 2012
P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease
F Sáez-Orellana, MC Fuentes-Fuentes, PA Godoy, T Silva-Grecchi, ...
Neuropharmacology 128, 366-378, 2018
Modulation of the neuronal network activity by P2X receptors and their involvement in neurological disorders
F Saez-Orellana, PA Godoy, T Silva-Grecchi, KM Barra, J Fuentealba
Pharmacological research 101, 109-115, 2015
Modulation of neuronal nicotinic receptor by quinolizidine alkaloids causes neuroprotection on a cellular Alzheimer model
JA Araya, AE Ramírez, D Figueroa-Aroca, GJ Sotes, C Pérez, J Becerra, ...
Journal of Alzheimer's Disease 42 (1), 143-155, 2014
Alzheimer’s Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α
F Sáez-Orellana, JN Octave, N Pierrot
Cells 9 (5), 1215, 2020
A natural benzofuran from the patagonic aleurodiscus vitellinus fungus has potent neuroprotective properties on a cellular model of amyloid-β peptide toxicity
M González-Ramírez, J Gavilán, T Silva-Grecchi, D Cajas-Madriaga, ...
Journal of Alzheimer's Disease 61 (4), 1463-1475, 2018
Microglial activation modulated by P2X4R in ischemia and repercussions in Alzheimer’s Disease
C Castillo, F Saez-Orellana, PA Godoy, J Fuentealba
Frontiers in Physiology 13, 814999, 2022
Neuroactive alkaloids that modulate the neuronal nicotinic receptor and provide neuroprotection in an Alzheimer's disease model: the case of: Teline monspessulana
J Fuentealba, F Saez-Orellana
Neural Regeneration Research 9 (21), 1880-1881, 2014
Regulation of PPARα by APP in Alzheimer disease impacts the pharmacological modulation of synaptic activity
F Sáez-Orellana, T Leroy, F Ribeiro, A Kreis, K Leroy, F Lalloyer, E Baugé, ...
JCI Insight, 2021
Neuroprotective Properties of Eudesmin on a Cellular Model of Amyloid-β Peptide Toxicity
C Castillo, G Bravo-Arrepol, A Wendt, F Saez-Orellana, C Millar, ...
Journal of Alzheimer's Disease, 1-12, 2022
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Articles 1–12