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David Fidock
David Fidock
Professor of Microbiology & Immunology and of Medical Sciences (in Medicine), Columbia University
Verified email at columbia.edu - Homepage
Title
Cited by
Cited by
Year
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
DA Fidock, T Nomura, AK Talley, RA Cooper, SM Dzekunov, MT Ferdig, ...
Molecular cell 6 (4), 861-871, 2000
17712000
A molecular marker for chloroquine-resistant falciparum malaria
A Djimdé, OK Doumbo, JF Cortese, K Kayentao, S Doumbo, Y Diourté, ...
New England journal of medicine 344 (4), 257-263, 2001
12182001
Antimalarial drug discovery: efficacy models for compound screening
DA Fidock, PJ Rosenthal, SL Croft, R Brun, S Nwaka
Nature reviews Drug discovery 3 (6), 509-520, 2004
11032004
Spiroindolones, a potent compound class for the treatment of malaria
M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ...
science 329 (5996), 1175-1180, 2010
10732010
Malaria: progress, perils, and prospects for eradication
BM Greenwood, DA Fidock, DE Kyle, SHI Kappe, PL Alonso, FH Collins, ...
The Journal of clinical investigation 118 (4), 1266-1276, 2008
9572008
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations
ABS Sidhu, D Verdier-Pinard, DA Fidock
Science 298 (5591), 210-213, 2002
9162002
K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates
J Straimer, NF Gnädig, B Witkowski, C Amaratunga, V Duru, ...
Science 347 (6220), 428-431, 2015
6552015
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
RT Eastman, DA Fidock
Nature Reviews Microbiology 7 (12), 864-874, 2009
5872009
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil
DA Fidock, TE Wellems
Proceedings of the National Academy of Sciences 94 (20), 10931-10936, 1997
5721997
A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms
D Ménard, N Khim, J Beghain, AA Adegnika, M Shafiul-Alam, O Amodu, ...
New England Journal of Medicine 374 (25), 2453-2464, 2016
4752016
Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin
ABS Sidhu, AC Uhlemann, SG Valderramos, JC Valderramos, S Krishna, ...
The Journal of infectious diseases 194 (4), 528-535, 2006
4752006
pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
ABS Sidhu, SG Valderramos, DA Fidock
Molecular microbiology 57 (4), 913-926, 2005
4492005
Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic
B Blasco, D Leroy, DA Fidock
Nature medicine 23 (8), 917-928, 2017
4132017
Targeting Plasmodium PI (4) K to eliminate malaria
CW McNamara, M Lee, CS Lim, SH Lim, J Roland, A Nagle, O Simon, ...
Nature 504 (7479), 248-253, 2013
3782013
A novel multiple-stage antimalarial agent that inhibits protein synthesis
B Baragaña, I Hallyburton, M Lee, NR Norcross, R Grimaldi, TD Otto, ...
Nature 522 (7556), 315-320, 2015
3512015
Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine …
RA Cooper, MT Ferdig, XZ Su, LMB Ursos, J Mu, T Nomura, H Fujioka, ...
Molecular pharmacology 61 (1), 35-42, 2002
3462002
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery
S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ...
Science 334 (6061), 1372-1377, 2011
3282011
Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda
A Uwimana, E Legrand, BH Stokes, JLM Ndikumana, M Warsame, ...
Nature medicine 26 (10), 1602-1608, 2020
3262020
Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data
MR Kuo, HR Morbidoni, D Alland, SF Sneddon, BB Gourlie, MM Staveski, ...
Journal of Biological Chemistry 278 (23), 20851-20859, 2003
3262003
A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study
B Witkowski, V Duru, N Khim, LS Ross, B Saintpierre, J Beghain, S Chy, ...
The Lancet Infectious Diseases 17 (2), 174-183, 2017
3062017
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