| An extended pyrrolobenzodiazepine–polyamide conjugate with selectivity for a DNA sequence containing the ICB2 transcription factor binding site F Brucoli, RM Hawkins, CH James, PJM Jackson, G Wells, TC Jenkins, ... Journal of medicinal chemistry 56 (16), 6339-6351, 2013 | 52 | 2013 |
| The Mycobactin biosynthesis pathway: A prospective therapeutic target in the battle against tuberculosis M Shyam, D Shilkar, H Verma, A Dev, BN Sinha, F Brucoli, S Bhakta, ... Journal of Medicinal Chemistry 64 (1), 71-100, 2020 | 42 | 2020 |
| Efficient synthesis and biological evaluation of proximicins A, B and C F Brucoli, A Natoli, P Marimuthu, MT Borrello, P Stapleton, S Gibbons, ... Bioorganic & medicinal chemistry 20 (6), 2019-2024, 2012 | 39 | 2012 |
| Novel C8-linked pyrrolobenzodiazepine (PBD)–heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box F Brucoli, RM Hawkins, CH James, G Wells, TC Jenkins, T Ellis, ... Bioorganic & medicinal chemistry letters 21 (12), 3780-3783, 2011 | 29 | 2011 |
| Structural characterization and antimicrobial evaluation of atractyloside, atractyligenin, and 15-didehydroatractyligenin methyl ester F Brucoli, MT Borrello, P Stapleton, GN Parkinson, S Gibbons Journal of Natural Products 75 (6), 1070-1075, 2012 | 19 | 2012 |
| DNA sequence-selective C8-linked pyrrolobenzodiazepine–heterocyclic polyamide conjugates show anti-tubercular-specific activities F Brucoli, JD Guzman, MA Basher, D Evangelopoulos, E McMahon, ... The Journal of Antibiotics 69 (12), 843-849, 2016 | 18 | 2016 |
| Synthesis, anti-mycobacterial activity and DNA sequence-selectivity of a library of biaryl-motifs containing polyamides F Brucoli, JD Guzman, A Maitra, CH James, KR Fox, S Bhakta Bioorganic & Medicinal Chemistry 23 (13), 3705-3711, 2015 | 15 | 2015 |
| Efficient solid-phase synthesis of a library of distamycin analogs containing novel biaryl motifs on SynPhase Lanterns F Brucoli, PW Howard, DE Thurston Journal of Combinatorial Chemistry 11 (4), 576-586, 2009 | 15 | 2009 |
| Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition M Shyam, H Verma, G Bhattacharje, P Mukherjee, S Singh, S Kamilya, ... Journal of Medicinal Chemistry 65 (1), 234-256, 2022 | 14 | 2022 |
| Integrated target‐based and phenotypic screening approaches for the identification of anti‐tubercular agents that bind to the mycobacterial adenylating enzyme MbtA L Ferguson, G Wells, S Bhakta, J Johnson, J Guzman, T Parish, ... ChemMedChem 14 (19), 1735-1741, 2019 | 11 | 2019 |
| Synthesis and biological evaluation of a novel C8-pyrrolobenzodiazepine (PBD) adenosine conjugate. A study on the role of the PBD ring in the biological activity of PBD-conjugates L Ferguson, S Bhakta, KR Fox, G Wells, F Brucoli Molecules 25 (5), 1243, 2020 | 7 | 2020 |
| Activity of DNA-targeted C8-linked pyrrolobenzodiazepine–heterocyclic polyamide conjugates against aerobically and hypoxically grown Mycobacterium tuberculosis under acidic and … A Iacobino, F Giannoni, L Fattorini, F Brucoli The Journal of Antibiotics 71 (9), 831-834, 2018 | 6 | 2018 |
| Novel C-3-(N-alkyl-aryl)-aminomethyl rifamycin SV derivatives exhibit activity against rifampicin-resistant Mycobacterium tuberculosis RpoBS522L strain and display a different … M Zloh, M Gupta, T Parish, F Brucoli European Journal of Medicinal Chemistry 225, 113734, 2021 | 5 | 2021 |
| 2-furyl (phenyl) methanol isolated from Atractilis gummifera rhizome exhibits anti-leishmanial activity S Deiva, L Ferguson, ME Rateb, R Williams, F Brucoli Fitoterapia 140, 104420, 2020 | 4 | 2020 |
| Rifamycins: do not throw the baby out with the bathwater. Is rifampicin still an effective anti-tuberculosis drug? F Brucoli, T D McHugh Future Medicinal Chemistry 13 (24), 2129-2131, 2021 | 3 | 2021 |
| Dissertation Project for the forensic science laboratory: Birch reduction of ephedrine and analysis of byproducts of forensic science interest KM Herrmann, R Murnane, F Brucoli Journal of Chemical Education 98 (5), 1750-1755, 2021 | 3 | 2021 |
| DNA-Minor Groove Binding Agents as Anti-Tubercular Probes. Old Tools for a New Challenge? F Brucoli Anti-Infective Agents 16 (2), 71-79, 2018 | 3 | 2018 |
| 526 A potent PBD-heterocyclic polyamide conjugate targeting an ICB2 transcription factor binding site F Brucoli, RM Hawkins, G Wells, TC Jenkins, T Ellis, M Kotecha, ... Ejc Supplements 7 (8), 168, 2010 | 2 | 2010 |
| Synthesis and antitubercular activity of novel 4-arylalkyl substituted thio-, oxy-and sulfoxy-quinoline analogues targeting the cytochrome bc1 complex R Murnane, M Zloh, S Tanna, R Allen, F Santana-Gomez, T Parish, ... Bioorganic Chemistry 138, 106659, 2023 | 1 | 2023 |
| Aminobenzofuran-containing analogues of proximicins exhibit higher antiproliferative activity against human UG-87 glioblastoma cells compared to temozolomide NS Madieh, S Tanna, NA Alqurayn, A Vaideanu, A Schatzlein, F Brucoli RSC advances 13 (12), 8420-8426, 2023 | 1 | 2023 |
