| A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms X Shu, V Lev-Ram, TJ Deerinck, Y Qi, EB Ramko, MW Davidson, Y Jin, ... PLoS biology 9 (4), e1001041, 2011 | 980 | 2011 |
| Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome X Shu, A Royant, MZ Lin, TA Aguilera, V Lev-Ram, PA Steinbach, ... Science 324 (5928), 804-807, 2009 | 824 | 2009 |
| The growing and glowing toolbox of fluorescent and photoactive proteins EA Rodriguez, RE Campbell, JY Lin, MZ Lin, A Miyawaki, AE Palmer, ... Trends in biochemical sciences 42 (2), 111-129, 2017 | 688 | 2017 |
| Novel Chromophores and Buried Charges Control Color in mFruits†,‡ X Shu, NC Shaner, CA Yarbrough, RY Tsien, SJ Remington Biochemistry 45 (32), 9639-9647, 2006 | 634 | 2006 |
| Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG YB Qi, EJ Garren, X Shu, RY Tsien, Y Jin Proceedings of the National Academy of Sciences 109 (19), 7499-7504, 2012 | 243 | 2012 |
| Enhancing serial block-face scanning electron microscopy to enable high resolution 3-D nanohistology of cells and tissues TJ Deerinck, EA Bushong, V Lev-Ram, X Shu, RY Tsien, MH Ellisman Microscopy and microanalysis 16 (S2), 1138-1139, 2010 | 240 | 2010 |
| A far-red fluorescent protein evolved from a cyanobacterial phycobiliprotein EA Rodriguez, GN Tran, LA Gross, JL Crisp, X Shu, JY Lin, RY Tsien Nature methods 13 (9), 763-769, 2016 | 226 | 2016 |
| Kindling Fluorescent Protein from Anemonia sulcata: Dark-State Structure at 1.38 Å Resolution, ML Quillin, DM Anstrom, X Shu, S O'Leary, K Kallio, DM Chudakov, ... Biochemistry 44 (15), 5774-5787, 2005 | 191 | 2005 |
| A naturally monomeric infrared fluorescent protein for protein labeling in vivo D Yu, MA Baird, JR Allen, ES Howe, MP Klassen, A Reade, K Makhijani, ... Nature methods 12 (8), 763-765, 2015 | 182 | 2015 |
| An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging D Yu, WC Gustafson, C Han, C Lafaye, M Noirclerc-Savoye, WP Ge, ... Nature communications 5 (1), 3626, 2014 | 180 | 2014 |
| Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry WH Guo, X Qi, X Yu, Y Liu, CI Chung, F Bai, X Lin, D Lu, L Wang, J Chen, ... Nature communications 11 (1), 4268, 2020 | 176 | 2020 |
| Visualizing dynamics of cell signaling in vivo with a phase separation-based kinase reporter Q Zhang, H Huang, L Zhang, R Wu, CI Chung, SQ Zhang, J Torra, ... Molecular cell 69 (2), 334-346. e4, 2018 | 169 | 2018 |
| Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo TL To, BJ Piggott, K Makhijani, D Yu, YN Jan, X Shu Proceedings of the National Academy of Sciences 112 (11), 3338-3343, 2015 | 101 | 2015 |
| Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy MT Butko, J Yang, Y Geng, HJ Kim, NL Jeon, X Shu, MR Mackey, ... Nature neuroscience 15 (12), 1742-1751, 2012 | 100 | 2012 |
| A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors HD Ou, W Kwiatkowski, TJ Deerinck, A Noske, KY Blain, HS Land, ... Cell 151 (2), 304-319, 2012 | 95 | 2012 |
| An alternative excited‐state proton transfer pathway in green fluorescent protein variant S205V X Shu, P Leiderman, R Gepshtein, NR Smith, K Kallio, D Huppert, ... Protein Science 16 (12), 2703-2710, 2007 | 93 | 2007 |
| Designing a green fluorogenic protease reporter by flipping a beta strand of GFP for imaging apoptosis in animals Q Zhang, A Schepis, H Huang, J Yang, W Ma, J Torra, SQ Zhang, L Yang, ... Journal of the American Chemical Society 141 (11), 4526-4530, 2019 | 88 | 2019 |
| Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D. 1. Mutagenesis and Structural Studies, X Shu, K Kallio, X Shi, P Abbyad, P Kanchanawong, W Childs, SG Boxer, ... Biochemistry 46 (43), 12005-12013, 2007 | 88 | 2007 |
| Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway CS Asensio, DW Sirkis, JW Maas, K Egami, TL To, FM Brodsky, X Shu, ... Developmental cell 27 (4), 425-437, 2013 | 85 | 2013 |
| Picking faces out of a crowd: genetic labels for identification of proteins in correlated light and electron microscopy imaging MH Ellisman, TJ Deerinck, X Shu, GE Sosinsky Methods in cell biology 111, 139-155, 2012 | 78 | 2012 |
