| Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing … M Alagumuthu, S Arumugam Bioorganic & Medicinal Chemistry 25 (4), 1448-1455, 2017 | 350* | 2017 |
| Computational approaches to develop isoquinoline based antibiotics through DNA gyrase inhibition mechanisms unveiled through antibacterial evaluation and molecular docking M Alagumuthu, VP Muralidharan, M Andrew, MH Ahmed, SK Iyer, ... Molecular Informatics 37 (12), 1800048, 2018 | 249* | 2018 |
| Discovery, synthesis and molecular substantiation of N-(benzo[d]thiazol-2-yl)-2-hydroxyquinoline-4-carboxamides as anticancer agents AM B. Bindu, S Vijayalakshmi Bioorganic Chemistry 91, 103171, doi: 10.1016/j.bioorg.2019.10317, 2019 | 225* | 2019 |
| An eco-friendly catalytic system for multicomponent, one-pot synthesis of novel spiro-chromeno indoline-triones and their anti-prostate cancer potentials evaluated via alkaline … MR Kumar, A Manikandan, A Sivakumar, VV Dhayabaran Bioorganic chemistry 81, 44-54, 2018 | 179* | 2018 |
| A sustainable synthesis of green carbon quantum dot (CQD) from Catharanthus roseus (white flowering plant) leaves and investigation of its dual fluorescence responsive behavior … T Arumugham, M Alagumuthu, RG Amimodu, S Munusamy, SK Iyer Sustainable materials and technologies 23, e00138, 2020 | 159* | 2020 |
| Synthesis and biological activities of nitro‐hydroxy‐phenylquinolines; validation of antibiotics effect over DNA gyrase inhibition and antimicrobial activity JD Bilavendran, A Manikandan, P Thangarasu, K Sivakumar Journal of Heterocyclic Chemistry, 2020 | 153* | 2020 |
| Therapeutic investigations of novel indoxyl-based indolines: A drug target validation and Structure-Activity Relationship of angiotensin-converting enzyme inhibitors with … A Manikandan, P Moharil, M Sathishkumar, C Muñoz-Garay, A Sivakumar European Journal of Medicinal Chemistry 141, 417-426, 2017 | 86* | 2017 |
| Identification of a potential peptide inhibitor of SARS-CoV-2 targeting its entry into the host cells MS Baig, M Alagumuthu, S Rajpoot, U Saqib Drugs in R&D 20, 161-169, 2020 | 84 | 2020 |
| Molecular explorations of substituted 2-(4-phenylquinolin-2-yl) phenols as phosphoinositide 3-kinase inhibitors and anticancer agents M Alagumuthu, S Arumugam Cancer chemotherapy and pharmacology 79, 389-397, 2017 | 72* | 2017 |
| Nanomaterials as a game changer in the management and treatment of diabetic foot ulcers MV Vellayappan, SK Jaganathan, A Manikandan RSC advances 6 (115), 114859-114878, 2016 | 63 | 2016 |
| Efficacy of phenyl quinoline phenol derivatives as COX-2 inhibitors; an approach to emergent the small molecules as the anti-inflammatory and analgesic therapeutics A Manikandan, S Ravichandran, KI Sathiyanarayanan, A Sivakumar Inflammopharmacology 25, 621-631, 2017 | 62* | 2017 |
| Synthesis of quinoline acetohydrazide-hydrazone derivatives evaluated as DNA gyrase inhibitors and potent antimicrobial agents P Sridhar, M Alagumuthu, S Arumugam, SR Reddy RSC advances 6 (69), 64460-64468, 2016 | 58 | 2016 |
| Dual Targeting of 3CLpro and PLpro of SARS-CoV-2: A Novel Structure-Based Design Approach to treat COVID-19 MSB Sajjan R, Manikandan A Current Research in Structural Biology 3, 9-18, 2021 | 54 | 2021 |
| N-substituted (E)-4-arylidene isoquinoline-1, 3-dione derivatives as potent anticancer agents–Synthesis and molecular evaluations A Manikandan, A Sivakumar Der Pharma Chemica 7 (12), 210-218, 2015 | 54* | 2015 |
| Pro-and Anti-Inflammatory Cytokine Expression Levels in Macrophages; An Approach to Develop Indazolpyridin-methanones as Novel Inflammation Medication M Alagumuthu, V Srivastava, M Shah, S Arumugam, M Sonaimuthu, ... Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 19 (4), 425-435, 2020 | 51* | 2020 |
| An investigation on the molecular structure, interaction with metal clusters, anti-Covid-19 ability of 2-deoxy-D-glucose: DFT calculations, MD and docking simulations G Venkatesh, Y Sixto-López, P Vennila, YS Mary, J Correa-Basurto, ... Journal of Molecular Structure 1258, 132678, 2022 | 49 | 2022 |
| Synthesis, DFT calculations, biological investigation, molecular docking studies of β-lactam derivatives A Mermer, H Bayrak, S Alyar, M Alagumuthu Journal of Molecular Structure 1208, 127891, 2020 | 39 | 2020 |
| Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies A Mermer, O Faiz, A Demirbas, N Demirbas, M Alagumuthu, S Arumugam Bioorganic Chemistry 85, 308-318, 2019 | 39 | 2019 |
| Drug repurposing of novel quinoline acetohydrazide derivatives as potent COX-2 inhibitors and anti-cancer agents CS Manohar, A Manikandan, P Sridhar, A Sivakumar, BS Kumar, ... Journal of Molecular Structure 1154, 437-444, 2018 | 34 | 2018 |
| Synthesis and discovery of pyrazolo-pyridine analogs as inflammation medications through pro-and anti-inflammatory cytokine and COX-2 inhibition assessments JD Bilavendran, A Manikandan, P Thangarasu, K Sivakumar Bioorganic chemistry 94, 103484, 2020 | 30 | 2020 |
Sivakumar ArumugamProfessor, VIT UniversityVerified email at vit.ac.in
