Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1490 | 2022 |
A global overview of pleiotropy and genetic architecture in complex traits K Watanabe, S Stringer, O Frei, M Umiĉeviĉ Mirkov, C de Leeuw, ... Nature genetics 51 (9), 1339-1348, 2019 | 1028 | 2019 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 931 | 2021 |
Common brain disorders are associated with heritable patterns of apparent aging of the brain T Kaufmann, D van der Meer, NT Doan, E Schwarz, MJ Lund, I Agartz, ... Nature neuroscience 22 (10), 1617-1623, 2019 | 427 | 2019 |
RICOPILI: rapid imputation for COnsortias PIpeLIne M Lam, S Awasthi, HJ Watson, J Goldstein, G Panagiotaropoulou, ... Bioinformatics 36 (3), 930-933, 2020 | 300 | 2020 |
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation O Frei, D Holland, OB Smeland, AA Shadrin, CC Fan, S Maeland, ... Nature communications 10 (1), 2417, 2019 | 264 | 2019 |
Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence OB Smeland, S Bahrami, O Frei, A Shadrin, K O’Connell, J Savage, ... Molecular psychiatry 25 (4), 844-853, 2020 | 232 | 2020 |
The polygenic architecture of schizophrenia—rethinking pathogenesis and nosology OB Smeland, O Frei, AM Dale, OA Andreassen Nature Reviews Neurology 16 (7), 366-379, 2020 | 167 | 2020 |
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ... Biological psychiatry 91 (3), 313-327, 2022 | 166 | 2022 |
Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model D Holland, O Frei, R Desikan, CC Fan, AA Shadrin, OB Smeland, ... PLoS Genetics 16 (5), e1008612, 2020 | 153 | 2020 |
Bigartm: Open source library for regularized multimodal topic modeling of large collections K Vorontsov, O Frei, M Apishev, P Romov, M Dudarenko Analysis of Images, Social Networks and Texts: 4th International Conference …, 2015 | 148 | 2015 |
Discovery of shared genomic loci using the conditional false discovery rate approach OB Smeland, O Frei, A Shadrin, K O’Connell, CC Fan, S Bahrami, ... Human genetics 139 (1), 85-94, 2020 | 140 | 2020 |
Understanding the genetic determinants of the brain with MOSTest D van der Meer, O Frei, T Kaufmann, AA Shadrin, A Devor, OB Smeland, ... Nature communications 11 (1), 3512, 2020 | 139 | 2020 |
Identification of genetic loci jointly influencing schizophrenia risk and the cognitive traits of verbal-numerical reasoning, reaction time, and general cognitive function OB Smeland, O Frei, K Kauppi, WD Hill, W Li, Y Wang, F Krull, F Bettella, ... JAMA psychiatry 74 (10), 1065-1075, 2017 | 127 | 2017 |
Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes D Van der Meer, J Rokicki, T Kaufmann, A Córdova-Palomera, ... Molecular psychiatry 25 (11), 3053-3065, 2020 | 118 | 2020 |
Shared genetic loci between body mass index and major psychiatric disorders: a genome-wide association study S Bahrami, NE Steen, A Shadrin, K O’Connell, O Frei, F Bettella, ... JAMA psychiatry 77 (5), 503-512, 2020 | 113 | 2020 |
Genetic overlap between schizophrenia and volumes of hippocampus, putamen, and intracranial volume indicates shared molecular genetic mechanisms OB Smeland, Y Wang, O Frei, W Li, DP Hibar, B Franke, F Bettella, ... Schizophrenia bulletin 44 (4), 854-864, 2018 | 106 | 2018 |
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications OA Andreassen, GFL Hindley, O Frei, OB Smeland World Psychiatry 22 (1), 4-24, 2023 | 89 | 2023 |
The genetic architecture of human cortical folding D Van Der Meer, T Kaufmann, AA Shadrin, C Makowski, O Frei, D Roelfs, ... Science advances 7 (51), eabj9446, 2021 | 77 | 2021 |
Genome-wide association analysis of Parkinson’s disease and schizophrenia reveals shared genetic architecture and identifies novel risk loci OB Smeland, A Shadrin, S Bahrami, I Broce, M Tesli, O Frei, KV Wirgenes, ... Biological psychiatry 89 (3), 227-235, 2021 | 68 | 2021 |