Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities M Tukulula, R Hayeshi, P Fonteh, D Meyer, A Ndamase, MT Madziva, ... Pharmaceutical research 32, 2713-2726, 2015 | 60 | 2015 |
Synthesis and antiplasmodial and antimycobacterial evaluation of new nitroimidazole and nitroimidazooxazine derivatives M Tukulula, RK Sharma, M Meurillon, A Mahajan, K Naran, D Warner, ... ACS Medicinal Chemistry Letters 4 (1), 128-131, 2013 | 56 | 2013 |
In vitro evaluation of chloroquine-loaded and heparin surface-functionalized solid lipid nanoparticles JO Muga, JW Gathirwa, M Tukulula, WGZO Jura Malaria journal 17, 1-7, 2018 | 48 | 2018 |
The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives M Tukulula, S Little, J Gut, PJ Rosenthal, B Wan, SG Franzblau, K Chibale European journal of medicinal chemistry 57, 259-267, 2012 | 46 | 2012 |
Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents M Tukulula, M Njoroge, GC Mugumbate, J Gut, PJ Rosenthal, S Barteau, ... Bioorganic & medicinal chemistry 21 (17), 4904-4913, 2013 | 30 | 2013 |
Synthesis, characterization and optimization of poly(p-phenylenediamine)-based organoclay composite for Cr(IV) remediation L Mdlalose, M Balogun, K Setshedi, M Tukulula, L Chimuka, A Chetty Applied Clay Science 139, 72-80, 2017 | 27 | 2017 |
Functionalization of PLGA Nanoparticles with 1, 3-β-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages M Tukulula, L Gouveia, P Paixao, R Hayeshi, B Naicker, A Dube Pharmaceutical research 35, 1-11, 2018 | 25 | 2018 |
Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds M Tukulula, M Njoroge, ET Abay, GC Mugumbate, L Wiesner, D Taylor, ... ACS medicinal chemistry letters 4 (12), 1198-1202, 2013 | 22 | 2013 |
New thiazolidine‐2, 4‐dione derivatives combined with organometallic ferrocene: Synthesis, structure and antiparasitic activity OO Oderinlo, M Tukulula, M Isaacs, HC Hoppe, D Taylor, VJ Smith, ... Applied Organometallic Chemistry 32 (7), e4385, 2018 | 19 | 2018 |
New quinoline–urea–benzothiazole hybrids as promising antitubercular agents: synthesis, in vitro antitubercular activity, cytotoxicity studies, and in silico ADME profiling R Moodley, C Mashaba, GH Rakodi, NB Ncube, MV Maphoru, ... Pharmaceuticals 15 (5), 576, 2022 | 14 | 2022 |
Indolizine Studies, Part 5: Indolizine-2-carboxamides as Potential HIV-1 Protease Inhibitors[ ] M Tukulula, R Klein, PT Kaye Synthetic Communications® 40 (13), 2018-2028, 2010 | 14 | 2010 |
A sustainable molybdenum oxide loaded on zirconia (MoO3/ZrO2) catalysed multicomponent reaction to synthesise novel dihydropyridines NP Hadebe, N Kerru, M Tukulula, SB Jonnalagadda Sustainable Chemistry and Pharmacy 25, 100578, 2022 | 8 | 2022 |
Strong base-or acid-mediated chemoselectivity shifts in the synthesis of 2H-chromene or coumarin derivatives from common Baylis-Hillman adducts TO Olomola, M Tukulula, R Klein, PT Kaye Tetrahedron 71 (29), 4868-4873, 2015 | 8 | 2015 |
Synthesis and in vitro antiprotozoan evaluation of 4-/8-aminoquinoline-based lactams and tetrazoles M Tukulula, S Louw, M Njoroge, K Chibale Molecules 25 (24), 5941, 2020 | 3 | 2020 |
The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic … ET Abay, JH van der Westhuizen, KJ Swart, L Gibhard, M Tukulula, ... Malaria journal 13, 1-13, 2014 | 3 | 2014 |
A critical analysis of the binding pocket of Plasmodium falciparum Phosphatidylinositol‐4‐kinase enzyme NB Ncube, KK Govender, M Tukulula ChemistrySelect 8 (43), e202302189, 2023 | 1 | 2023 |
Hydrazone‐Tethered 5‐(Pyridin‐4‐yl)‐4H‐1,2,4‐triazole‐3‐thiol Hybrids: Synthesis, Characterisation, in silico ADME Studies, and in vitro Antimycobacterial … OO Oderinlo, A Jordaan, R Seldon, M Isaacs, HC Hoppe, DF Warner, ... ChemMedChem 18 (6), e202200572, 2023 | 1 | 2023 |
Discovery of Novel Thiazolidinedione-Derivatives with Multi-Modal Antidiabetic Activities In Vitro and In Silico C Arineitwe, O Oderinlo, M Tukulula, S Khanye, A Khathi, N Sibiya International Journal of Molecular Sciences 24 (3), 3024, 2023 | 1 | 2023 |
Synthesis, stereochemistry and in vitro STD NMR and in silico HIV-1 PR enzyme-binding potential of MBH-derived inhibitors M Tukulula, IA Olasupo, GC Mugumbate, KA Lobb, R Klein, Y Sayed, ... Journal of Molecular Structure 1268, 133716, 2022 | 1 | 2022 |
Leveraging computational tools to combat malaria: assessment and development of new therapeutics NB Ncube, M Tukulula, KG Govender Journal of Cheminformatics 16 (1), 1-14, 2024 | | 2024 |