Leifu Chang
Leifu Chang
Department of Biological Sciences, Purdue University
Verified email at purdue.edu
Cited by
Cited by
Cellular internalization of exosomes occurs through phagocytosis
D Feng, WL Zhao, YY Ye, XC Bai, RQ Liu, LF Chang, Q Zhou, SF Sui
Traffic 11 (5), 675-687, 2010
Atomic structure of the APC/C and its mechanism of protein ubiquitination
L Chang, Z Zhang, J Yang, SH McLaughlin, D Barford
Nature 522 (7557), 450-454, 2015
Molecular architecture and mechanism of the anaphase-promoting complex
L Chang, Z Zhang, J Yang, SH McLaughlin, D Barford
Nature 513 (7518), 388-393, 2014
Molecular mechanism of APC/C activation by mitotic phosphorylation
S Zhang, L Chang, C Alfieri, Z Zhang, J Yang, S Maslen, M Skehel, ...
Nature 533 (7602), 260-264, 2016
Molecular basis of APC/C regulation by the spindle assembly checkpoint
C Alfieri, L Chang, Z Zhang, J Yang, S Maslen, M Skehel, D Barford
Nature 536 (7617), 431-436, 2016
Insights into the anaphase-promoting complex: a molecular machine that regulates mitosis
L Chang, D Barford
Current opinion in structural biology 29, 1-9, 2014
Structural organization of an intact phycobilisome and its association with photosystem II
L Chang, X Liu, Y Li, CC Liu, F Yang, J Zhao, SF Sui
Cell research 25 (6), 726-737, 2015
Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
C Alfieri, L Chang, D Barford
Nature 559 (7713), 274-278, 2018
Bowl-shaped oligomeric structures on membranes as DegP's new functional forms in protein quality control
QT Shen, XC Bai, LF Chang, Y Wu, HW Wang, SF Sui
Proceedings of the National Academy of Sciences 106 (12), 4858-4863, 2009
Cryo-EM structure of a metazoan separase–securin complex at near-atomic resolution
A Boland, TG Martin, Z Zhang, J Yang, X Bai, L Chang, SHW Scheres, ...
Nature structural & molecular biology 24 (4), 414-418, 2017
Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome
K Yan, J Yang, Z Zhang, SH McLaughlin, L Chang, D Fasci, ...
Nature 574 (7777), 278-282, 2019
Structural characterization of full-length NSF and 20S particles
LF Chang, S Chen, CC Liu, X Pan, J Jiang, XC Bai, X Xie, HW Wang, ...
Nature structural & molecular biology 19 (3), 268-275, 2012
Structural basis for the inhibition of CRISPR-Cas12a by anti-CRISPR proteins
H Zhang, Z Li, CM Daczkowski, C Gabel, AD Mesecar, L Chang
Cell host & microbe 25 (6), 815-826. e4, 2019
Characterization of the structure and function of Escherichia coli DegQ as a representative of the DegQ-like proteases of bacterial HtrA family proteins
X Bai, X Pan, X Wang, Y Ye, L Chang, D Leng, J Lei, SF Sui
Structure 19 (9), 1328-1337, 2011
The potential of cryo-electron microscopy for structure-based drug design
A Boland, L Chang, D Barford
Essays in biochemistry 61 (5), 543-560, 2017
The four canonical TPR subunits of human APC/C form related homo-dimeric structures and stack in parallel to form a TPR suprahelix
Z Zhang, L Chang, J Yang, N Conin, K Kulkarni, D Barford
Journal of molecular biology 425 (22), 4236-4248, 2013
Structure of the DOCK2− ELMO1 complex provides insights into regulation of the auto-inhibited state
L Chang, J Yang, CH Jo, A Boland, Z Zhang, SH McLaughlin, ...
Nature communications 11 (1), 1-17, 2020
WD40 domain of Apc1 is critical for the coactivator-induced allosteric transition that stimulates APC/C catalytic activity
Q Li, L Chang, S Aibara, J Yang, Z Zhang, D Barford
Proceedings of the National Academy of Sciences 113 (38), 10547-10552, 2016
Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain
NB Cronin, J Yang, Z Zhang, K Kulkarni, L Chang, H Yamano, D Barford
Journal of molecular biology 427 (20), 3300-3315, 2015
Cryo-EM structure of the RNA-guided ribonuclease Cas12g
Z Li, H Zhang, R Xiao, R Han, L Chang
Nature Chemical Biology 17 (4), 387-393, 2021
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