The physiology and pathophysiology of nitric oxide in the brain FX Guix, I Uribesalgo, M Coma, FJ Munoz Progress in neurobiology 76 (2), 126-152, 2005 | 922 | 2005 |
The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer’s disease S Miranda, C Opazo, LF Larrondo, FJ Muñoz, F Ruiz, F Leighton, ... Progress in neurobiology 62 (6), 633-648, 2000 | 517 | 2000 |
Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer’s fibrils A Alvarez, R Alarcon, C Opazo, EO Campos, FJ Munoz, FH Calderon, ... Journal of Neuroscience 18 (9), 3213-3223, 1998 | 436 | 1998 |
The blood-brain barrier: structure, function and therapeutic approaches to cross it M Tajes, E Ramos-Fernández, X Weng-Jiang, M Bosch-Morató, ... Molecular membrane biology 31 (5), 152-167, 2014 | 325 | 2014 |
Trolox and 17β-estradiol protect against amyloid β-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway RA Quintanilla, FJ Munoz, MJ Metcalfe, M Hitschfeld, G Olivares, ... Journal of biological chemistry 280 (12), 11615-11625, 2005 | 173 | 2005 |
Hemizygosity at the NCF1 gene in patients with Williams-Beuren syndrome decreases their risk of hypertension M Del Campo, A Antonell, LF Magano, FJ Muñoz, R Flores, M Bayés, ... The American Journal of Human Genetics 78 (4), 533-542, 2006 | 136 | 2006 |
CB 1 agonist ACEA protects neurons and reduces the cognitive impairment of AβPP/PS1 mice E Aso, E Palomer, S Juvés, R Maldonado, FJ Muñoz, I Ferrer Journal of Alzheimer's disease 30 (2), 439-459, 2012 | 134 | 2012 |
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation FX Guix, G Ill-Raga, R Bravo, T Nakaya, G de Fabritiis, M Coma, ... Brain 132 (5), 1335-1345, 2009 | 122 | 2009 |
Neurotoxicity of acetylcholinesterase amyloid β-peptide aggregates is dependent on the type of Aβ peptide and the AChE concentration present in the complexes FJ Muñoz, NC Inestrosa FEBS letters 450 (3), 205-209, 1999 | 121 | 1999 |
Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase‐amyloid complexes AB Bonnefont, FJ Muñoz, NC Inestrosa FEBS letters 441 (2), 220-224, 1998 | 120 | 1998 |
PC12 and neuro 2a cells have different susceptibilities to acetylcholinesterase–amyloid complexes, amyloid25–35 fragment, glutamate, and hydrogen peroxide FH Calderón, A Bonnefont, FJ Muñoz, V Fernández, LA Videla, ... Journal of neuroscience research 56 (6), 620-631, 1999 | 95 | 1999 |
The structure and function of actin cytoskeleton in mature glutamatergic dendritic spines A Bellot, B Guivernau, M Tajes, M Bosch-Morato, V Valls-Comamala, ... Brain research 1573, 1-16, 2014 | 88 | 2014 |
Modification of γ‐secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease FX Guix, T Wahle, K Vennekens, A Snellinx, L Chávez‐Gutiérrez, ... EMBO molecular medicine 4 (7), 660-673, 2012 | 88 | 2012 |
Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase FJ Muñoz, R Aldunate, NC Inestrosa Neuroreport 10 (17), 3621-3625, 1999 | 84 | 1999 |
Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons A Klein, C Maldonado, LM Vargas, M Gonzalez, F Robledo, KP de Arce, ... Neurobiology of disease 41 (1), 209-218, 2011 | 77 | 2011 |
Oxidative stress triggers the amyloidogenic pathway in human vascular smooth muscle cells M Coma, FX Guix, G Ill-Raga, I Uribesalgo, F Alameda, MA Valverde, ... Neurobiology of aging 29 (7), 969-980, 2008 | 77 | 2008 |
Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression G Ill-Raga, E Palomer, MA Wozniak, E Ramos-Fernández, ... PLoS One 6 (6), e21456, 2011 | 76 | 2011 |
Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells G Ill-Raga, E Ramos-Fernández, FX Guix, M Tajes, M Bosch-Morató, ... Journal of Alzheimer's Disease 22 (2), 641-652, 2010 | 72 | 2010 |
Vitamin E but not 17β-estradiol protects against vascular toxicity induced by β-amyloid wild type and the Dutch amyloid variant FJ Munoz, C Opazo, G Gil-Gómez, G Tapia, V Fernández, MA Valverde, ... Journal of Neuroscience 22 (8), 3081-3089, 2002 | 64 | 2002 |
Methylglyoxal reduces mitochondrial potential and activates Bax and caspase-3 in neurons: Implications for Alzheimer's disease M Tajes, A Eraso-Pichot, F Rubio-Moscardó, B Guivernau, ... Neuroscience letters 580, 78-82, 2014 | 63 | 2014 |