| Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1 S Hacein-Bey-Abina, A Garrigue, GP Wang, J Soulier, A Lim, E Morillon, ... The Journal of clinical investigation 118 (9), 3132-3142, 2008 | 2155 | 2008 |
| Efficacy of gene therapy for X-linked severe combined immunodeficiency S Hacein-Bey-Abina, J Hauer, A Lim, C Picard, GP Wang, CC Berry, ... New England Journal of Medicine 363 (4), 355-364, 2010 | 758 | 2010 |
| TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs J Hauer, S Püschner, P Ramakrishnan, U Simon, M Bongers, C Federle, ... Proceedings of the National Academy of Sciences 102 (8), 2874-2879, 2005 | 307 | 2005 |
| Childhood cancer predisposition syndromes—a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology T Ripperger, SS Bielack, A Borkhardt, IB Brecht, B Burkhardt, ... American journal of medical genetics Part A 173 (4), 1017-1037, 2017 | 299 | 2017 |
| Infection Exposure Is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility A Martin-Lorenzo, J Hauer, C Vicente-Duenas, F Auer, ... Cancer discovery 5 (12), 1328-1343, 2015 | 145 | 2015 |
| A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells S Zhou, D Mody, SS DeRavin, J Hauer, T Lu, Z Ma, S Hacein-Bey Abina, ... Blood, The Journal of the American Society of Hematology 116 (6), 900-908, 2010 | 143 | 2010 |
| Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c. 547G> A F Auer, F Rüschendorf, M Gombert, P Husemann, S Ginzel, S Izraeli, ... Leukemia 28 (5), 1136-1138, 2014 | 100 | 2014 |
| Epigenetic priming in cancer initiation C Vicente-Dueñas, J Hauer, C Cobaleda, A Borkhardt, I Sánchez-García Trends in cancer 4 (6), 408-417, 2018 | 94 | 2018 |
| Effective treatment of kaposiform hemangioendotheliomas associated with Kasabach–Merritt phenomenon using four‐drug regimen J Hauer, U Graubner, N Konstantopoulos, S Schmidt, T Pfluger, I Schmid Pediatric Blood & Cancer 49 (6), 852-854, 2007 | 90 | 2007 |
| Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases G Rodríguez-Hernández, J Hauer, A Martín-Lorenzo, D Schäfer, ... Cancer Research 77 (16), 4365-4377, 2017 | 88 | 2017 |
| An intact gut microbiome protects genetically predisposed mice against leukemia C Vicente-Dueñas, S Janssen, M Oldenburg, F Auer, I González-Herrero, ... Blood, The Journal of the American Society of Hematology 136 (18), 2003-2017, 2020 | 81 | 2020 |
| Discovery of the first-in-class dual histone deacetylase–proteasome inhibitor S Bhatia, V Krieger, M Groll, JD Osko, N Reßing, H Ahlert, A Borkhardt, ... Journal of medicinal chemistry 61 (22), 10299-10309, 2018 | 69 | 2018 |
| Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response S Bhatia, D Diedrich, B Frieg, H Ahlert, S Stein, B Bopp, F Lang, T Zang, ... Blood, The Journal of the American Society of Hematology 132 (3), 307-320, 2018 | 68 | 2018 |
| Recombination-activating gene 1 (Rag1)–deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome NP van Til, R Sarwari, TP Visser, J Hauer, C Lagresle-Peyrou, ... Journal of allergy and clinical immunology 133 (4), 1116-1123, 2014 | 62 | 2014 |
| Stable and functional lymphoid reconstitution in artemis-deficient mice following lentiviral artemis gene transfer into hematopoietic stem cells F Benjelloun, A Garrigue, C Demerens-de Chappedelaine, ... Molecular Therapy 16 (8), 1490-1499, 2008 | 62 | 2008 |
| Loss of Pax5 Exploits Sca1-BCR-ABLp190 Susceptibility to Confer the Metabolic Shift Essential for pB-ALL A Martín-Lorenzo, F Auer, LN Chan, I García-Ramírez, I Gonzalez-Herrero, ... Cancer research 78 (10), 2669-2679, 2018 | 47 | 2018 |
| Lmo2 expression defines tumor cell identity during T‐cell leukemogenesis I García‐Ramírez, S Bhatia, G Rodríguez‐Hernández, I González‐Herrero, ... The EMBO journal 37 (14), e98783, 2018 | 39 | 2018 |
| Comprehensive germline-genomic and clinical profiling in 160 unselected children and adolescents with cancer R Wagener, J Taeubner, C Walter, L Yasin, D Alzoubi, C Bartenhagen, ... European Journal of Human Genetics 29 (8), 1301-1311, 2021 | 37 | 2021 |
| Toward prevention of childhood ALL by early-life immune training J Hauer, U Fischer, A Borkhardt Blood, The Journal of the American Society of Hematology 138 (16), 1412-1428, 2021 | 34 | 2021 |
| Multicomponent Synthesis, Binding Mode, and Structure–Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups N Reßing, M Sönnichsen, JD Osko, A Schöler, J Schliehe-Diecks, ... Journal of medicinal chemistry 63 (18), 10339-10351, 2020 | 34 | 2020 |
