Diego A Oyarzún

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Guy-Bart StanProfessor of BioSystems Engineering and Control, RAEng Chair, Bioengineering, Imperial CollegeVerified email at imperial.ac.uk
Ahmad Abdullah MannanResearch Associate, Department of BioengineeringVerified email at imperial.ac.uk
Andrea Y. WeißeUniversity of EdinburghVerified email at ed.ac.uk
Fuzhong ZhangProfessor, Washington University in St. LouisVerified email at seas.wustl.edu
Madalena ChavesINRIA Sophia AntipolisVerified email at inria.fr
Di LiuSandia National Laboratories, Washington University in St. LouisVerified email at wustl.edu
Richard MiddletonProfessor, University of NewcastleVerified email at newcastle.edu.au
Jesús PicóProfessor of Automatic Control, Universitat Politècnica de ValènciaVerified email at ai2.upv.es
Fernando López-CaamalUniversidad de GuanajuatoVerified email at ugto.mx
Steffen WaldherrUniversity of ViennaVerified email at univie.ac.at
Vincent DanosDirecteur de Recherches CNRS Ecole Normale SupérieureVerified email at ens.fr
Peter SwainUniversity of EdinburghVerified email at ed.ac.uk
Jean-Baptiste LugagneBoston UniversityVerified email at bu.edu
Ben-Fillippo KrippendorffVerified email at roche.com
Jose RodriguezProfessor, Engineering Faculty, Universidad San SebastianVerified email at uss.cl
Pablo LezanaUniversidad Técnica Federico Santa MariaVerified email at usm.cl
Brian P IngallsProfessor of Applied Mathematics, University of WaterlooVerified email at uwaterloo.ca
Míriam R. GarcíaTenured Scientist. Biosystems & Bioprocess Engineering. IIM-CSICVerified email at iim.csic.es
Alejandro VignoniResearch Scientist, Synthetic Biology and Biosystems Control Group - Univesitat Politécnica deVerified email at upv.es
Andres PetersFaculty of Engineering and Sciences, Universidad Adolfo IbáñezVerified email at uai.cl

Diego A Oyarzún

University of Edinburgh, Alan Turing Institute

Verified email at ed.ac.uk - Homepage

Machine learning control theory systems biology synthetic biology theoretical biology


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Mechanistic links between cellular trade-offs, gene expression, and growth AY Weiße, DA Oyarzún, V Danos, PS Swain Proceedings of the National Academy of Sciences 112 (9), E1038-E1047, 2015	374	2015
Cascaded multilevel inverter with regeneration capability and reduced number of switches P Lezana, J Rodríguez, DA Oyarzún IEEE Transactions on Industrial Electronics 55 (3), 1059-1066, 2008	296	2008
Fundamental design principles for transcription-factor-based metabolite biosensors AA Mannan, D Liu, F Zhang, DA Oyarzún ACS synthetic biology 6 (10), 1851-1859, 2017	160	2017
Pathways to cellular supremacy in biocomputing L Grozinger, M Amos, TE Gorochowski, P Carbonell, DA Oyarzún, R Stoof, ... Nature communications 10 (1), 5250, 2019	108	2019
The power of synthetic biology for bioproduction, remediation and pollution control V Lorenzo, KL Prather, G Chen, E O’Day, C Kameke, DA Oyarzún, ... EMBO Rep 19 (4), 4-9, 2018	103*	2018
Dynamic optimization of metabolic networks coupled with gene expression S Waldherr, DA Oyarzún, A Bockmayr Journal of theoretical biology 365, 469-485, 2015	96	2015
Dynamic metabolic control: towards precision engineering of metabolism D Liu, AA Mannan, Y Han, DA Oyarzún, F Zhang Journal of Industrial Microbiology and Biotechnology 45 (7), 535-543, 2018	87	2018
Noise propagation in synthetic gene circuits for metabolic control DA Oyarzún, JB Lugagne, GBV Stan ACS synthetic biology 4 (2), 116-125, 2015	83	2015
Synthetic gene circuits for metabolic control: design trade-offs and constraints DA Oyarzún, GBV Stan Journal of The Royal Society Interface 10 (78), 20120671, 2013	73	2013
Sequential activation of metabolic pathways: a dynamic optimization approach DA Oyarzún, BP Ingalls, RH Middleton, D Kalamatianos Bulletin of mathematical biology 71 (8), 1851-1872, 2009	55	2009
Growth defects and loss-of-function in synthetic gene circuits EM Nikolados, AY Weiße, F Ceroni, DA Oyarzún ACS synthetic biology 8 (6), 1231-1240, 2019	53	2019
Stochastic modelling reveals mechanisms of metabolic heterogeneity MK Tonn, P Thomas, M Barahona, DA Oyarzún Communications biology 2 (1), 108, 2019	41	2019
Multistability and oscillations in genetic control of metabolism DA Oyarzún, M Chaves, M Hoff-Hoffmeyer-Zlotnik Journal of Theoretical Biology 295, 139-153, 2012	38	2012
Shaping Pulses to Control Bistable Systems: Analysis, Computation and Counterexamples A Sootla, DA Oyarzun, D Angeli, GB Stan Automatica 63, 254-264, 2016	37	2016
Flux-dependent graphs for metabolic networks M Beguerisse-Díaz, G Bosque, D Oyarzún, J Picó, M Barahona NPJ systems biology and applications 4 (1), 32, 2018	34	2018
A stochastic model of gene expression with polymerase recruitment and pause release Z Cao, T Filatova, DA Oyarzún, R Grima Biophysical Journal 119 (5), 1002-1014, 2020	32*	2020
Design of a bistable switch to control cellular uptake DA Oyarzún, M Chaves Journal of The Royal Society Interface 12 (113), 20150618, 2015	30	2015
Dynamics of complex feedback architectures in metabolic pathways M Chaves, DA Oyarzún Automatica 99, 323-332, 2019	22	2019
Control of protein concentrations in heterogeneous cell populations A Vignoni, DA Oyarzún, J Picó, GB Stan Control Conference (ECC), 2013 European, 3633-3639, 2013	22	2013
Predicting the F (ab)-mediated effect of monoclonal antibodies in vivo by combining cell-level kinetic and pharmacokinetic modelling BF Krippendorff, DA Oyarzún, W Huisinga Journal of pharmacokinetics and pharmacodynamics 39, 125-139, 2012	22	2012

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