Comprehensive analysis of heterochromatin-and RNAi-mediated epigenetic control of the fission yeast genome HP Cam, T Sugiyama, ES Chen, X Chen, PC FitzGerald, SIS Grewal Nature genetics 37 (8), 809-819, 2005 | 581 | 2005 |
Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast K Takahashi, ES Chen, M Yanagida Science 288 (5474), 2215-2219, 2000 | 445 | 2000 |
Cell cycle control of centromeric repeat transcription and heterochromatin assembly ES Chen, K Zhang, E Nicolas, HP Cam, M Zofall, SIS Grewal Nature 451 (7179), 734-737, 2008 | 417 | 2008 |
A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast ES Chen, S Saitoh, M Yanagida, K Takahashi Molecular cell 11 (1), 175-187, 2003 | 152 | 2003 |
Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin FE Reyes-Turcu, K Zhang, M Zofall, E Chen, SIS Grewal Nature structural & molecular biology 18 (10), 1132-1138, 2011 | 143 | 2011 |
Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function H Murakami, DB Goto, T Toda, ES Chen, SI Grewal, RA Martienssen, ... PLoS One 2 (3), e317, 2007 | 94 | 2007 |
Transcriptional scaffolds for heterochromatin assembly HP Cam, ES Chen, SIS Grewal Cell 136 (4), 610-614, 2009 | 82 | 2009 |
Cellular factories for coenzyme Q10 production SQE Lee, TS Tan, M Kawamukai, ES Chen Microbial cell factories 16, 1-16, 2017 | 76 | 2017 |
Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin ES Chen, T Sutani, M Yanagida Proceedings of the National Academy of Sciences 101 (21), 8078-8083, 2004 | 49 | 2004 |
cGAS-STING pathway in oncogenesis and cancer therapeutics BY Da Hoong, YH Gan, H Liu, ES Chen Oncotarget 11 (30), 2930, 2020 | 43 | 2020 |
NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity C Li, Y Zhang, Q Yang, F Ye, SY Sun, ES Chen, YC Liou Scientific reports 6 (1), 18773, 2016 | 42 | 2016 |
Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs RA Jackson, ES Chen Pharmacology & therapeutics 162, 69-85, 2016 | 37 | 2016 |
Predicting chemotherapeutic drug combinations through gene network profiling TTT Nguyen, JKK Chua, KS Seah, SH Koo, JY Yee, EG Yang, KK Lim, ... Scientific Reports 6 (1), 18658, 2016 | 26 | 2016 |
Structural and functional specificity of H3K36 methylation UTF Lam, BKY Tan, JJX Poh, ES Chen Epigenetics & Chromatin 15 (1), 17, 2022 | 25 | 2022 |
Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast Z Tay, RJ Eng, K Sajiki, KK Lim, MY Tang, M Yanagida, ES Chen PLoS One 8 (1), e55041, 2013 | 23 | 2013 |
Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast TTT Nguyen, JSL Lim, RMY Tang, L Zhang, ES Chen Scientific reports 5 (1), 8400, 2015 | 22 | 2015 |
SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling KS Seah, JY Loh, TTT Nguyen, HL Tan, PE Hutchinson, KK Lim, ... Experimental Cell Research 370 (2), 283-291, 2018 | 21 | 2018 |
Synthetic combinations of missense polymorphic genetic changes underlying Down syndrome susceptibility RA Jackson, ML Nguyen, AN Barrett, YY Tan, MA Choolani, ES Chen Cellular and molecular life sciences 73, 4001-4017, 2016 | 19 | 2016 |
Human genome meeting 2016: houston, TX, USA. 28 February-2 March 2016 AK Srivastava, Y Wang, R Huang, C Skinner, T Thompson, L Pollard, ... Human genomics 10, 1-40, 2016 | 17 | 2016 |
Histone H3 lysine 36 methyltransferase mobilizes NER factors to regulate tolerance against alkylation damage in fission yeast KK Lim, TTT Nguyen, AY Li, YP Yeo, ES Chen Nucleic acids research 46 (10), 5061-5074, 2018 | 16 | 2018 |