| Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart DF Dai, PP Karunadharma, YA Chiao, N Basisty, D Crispin, EJ Hsieh, ... Aging cell 13 (3), 529-539, 2014 | 325 | 2014 |
| Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration PP Karunadharma, CL Nordgaard, TW Olsen, DA Ferrington Investigative ophthalmology & visual science 51 (11), 5470-5479, 2010 | 250 | 2010 |
| Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration CL Nordgaard, PP Karunadharma, X Feng, TW Olsen, DA Ferrington Investigative ophthalmology & visual science 49 (7), 2848-2855, 2008 | 208 | 2008 |
| Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects PP Karunadharma, N Basisty, DF Dai, YA Chiao, EK Quarles, EJ Hsieh, ... Aging cell 14 (4), 547-557, 2015 | 102 | 2015 |
| Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease M Eshraghi, PP Karunadharma, J Blin, N Shahani, EP Ricci, A Michel, ... Nature communications 12 (1), 1461, 2021 | 78 | 2021 |
| Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration DA Ferrington, RJ Kapphahn, MM Leary, SR Atilano, MR Terluk, ... Experimental eye research 145, 269-277, 2016 | 76 | 2016 |
| Age modifies respiratory complex I and protein homeostasis in a muscle type‐specific manner SE Kruse, PP Karunadharma, N Basisty, R Johnson, RP Beyer, ... Aging Cell 15 (1), 89-99, 2016 | 75 | 2016 |
| Topograph, a software platform for precursor enrichment corrected global protein turnover measurements EJ Hsieh, NJ Shulman, DF Dai, ES Vincow, PP Karunadharma, ... Molecular & cellular proteomics 11 (11), 1468-1474, 2012 | 66 | 2012 |
| Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments PP Karunadharma, N Basisty, YA Chiao, DF Dai, R Drake, N Levy, ... The FASEB journal 29 (8), 3582, 2015 | 64 | 2015 |
| Mining naive rabbit antibody repertoires by phage display for monoclonal antibodies of therapeutic utility H Peng, T Nerreter, J Chang, J Qi, X Li, P Karunadharma, GJ Martinez, ... Journal of molecular biology 429 (19), 2954-2973, 2017 | 51 | 2017 |
| Stable isotope labeling reveals novel insights into ubiquitin-mediated protein aggregation with age, calorie restriction, and rapamycin treatment NB Basisty, Y Liu, J Reynolds, PP Karunadharma, DF Dai, J Fredrickson, ... The Journals of Gerontology: Series A 73 (5), 561-570, 2018 | 25 | 2018 |
| A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020 MH Tran, H Park, CL Nobles, P Karunadharma, L Pan, G Zhong, H Wang, ... Molecular Therapy-Nucleic Acids 24, 40-53, 2021 | 23 | 2021 |
| Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure DF Dai, Y Liu, N Basisty, P Karunadharma, SG Dastidar, YA Chiao, ... Geroscience 41, 847-860, 2019 | 15 | 2019 |
| Reprogramming of the heavy-chain CDR3 regions of a human antibody repertoire T Ou, W He, BD Quinlan, Y Guo, MH Tran, P Karunadharma, H Park, ... Molecular Therapy 30 (1), 184-197, 2022 | 10 | 2022 |
| Dissecting Regulators of Aging and Age-Related Macular Degeneration in the Retinal Pigment Epithelium PP Karunadharma, RJ Kapphahn, MR Stahl, TW Olsen, DA Ferrington Oxidative Medicine and Cellular Longevity 2022, 2022 | 8 | 2022 |
| Global ribosome profiling reveals that mutant huntingtin stalls ribosomes and represses protein synthesis independent of fragile X mental retardation protein M Eshraghi, P Karunadharma, J Blin, N Shahani, E Ricci, A Michel, ... BioRxiv, 629667, 2019 | 7 | 2019 |
| The Chromatin Regulator Mll1 Supports T Follicular Helper Cell Differentiation by Controlling Expression of Bcl6, LEF-1, and TCF-1 S Bélanger, S Haupt, CE Faliti, A Getzler, J Choi, H Diao, ... The Journal of Immunology 210 (11), 1752-1760, 2023 | 5 | 2023 |
| Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression O Rivera, M Sharma, S Dagar, N Shahani, UN Ramårez-Jarquån, ... Cellular and Molecular Life Sciences 81 (1), 169, 2024 | 4 | 2024 |
| Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny H Diao, R Chen, SM Tsuda, D Wang, MA Frederick, J Kim, ... bioRxiv, 2021.08. 11.456014, 2021 | 1 | 2021 |
| No association between cataract surgery and mitochondrial DNA damage with age-related macular degeneration in human donor eyes KR Armbrust, PP Karunadharma, MR Terluk, RJ Kapphahn, TW Olsen, ... PloS one 16 (10), e0258803, 2021 | | 2021 |
Michael MacCossProfessor of Genome Sciences, University of WashingtonVerified email at uw.edu
